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Eculizumab in low-middle income countries: how much does a life cost?
(2022-01-01)
Atypical hemolytic uremic syndrome (aHUS) is an ultra-rare disease and eculizumab was approved as first line therapy in 2011 by the Food and Drug Administration. Access to eculizumab in low-middle income countries is ...
Absence of interleukin-10 reduces progression of shiga toxin-induced hemolytic uremic syndrome
(Journal of the Serbian Chemical Society, 2021-02)
Hemolytic Uremic Syndrome (HUS), a disease triggered by Shiga toxin (Stx), is characterized by hemolytic anemia, thrombocytopenia and renal failure. The inflammatory response mediated by polymorphonuclear neutrophils (PMNs) ...
Atypical hemolytic uremic syndrome: a nationwide Colombian pediatric series
(Research Square Company, 2023)
Background
Atypical hemolytic uremic syndrome (aHUS) is a rare complement-mediated kidney disease with genetic
predisposition and represents up to 10% of pediatric hemolytic uremic syndrome (HUS) cases. Few studies ...
Relevance of bacteriophage 933W in the development of hemolytic uremic syndrome (HUS)
(Frontiers Research Foundation, 2018-12)
Hemolytic uremic syndrome (HUS), principally caused by Shiga toxins (Stxs), is associated with Shiga toxin-producing Escherichia coli (STEC) infections. We previously reported Stx2 expression by host cells in vitro and in ...
Soluble CD40 ligand and oxidative response are reciprocally stimulated during shiga toxin-associated hemolytic uremic syndrome
(MDPI AG, 2017-10-25)
Shiga toxin (Stx), produced by Escherichia coli, is the main pathogenic factor of diarrhea-associated hemolytic uremic syndrome (HUS), which is characterized by the obstruction of renal microvasculature by platelet-fibrin ...
Frequency of hospitalizations due to hemolytic uremic syndrome in children from 0 to 14 years of age in Peru, period 2015 to 2022Frecuencia de hospitalizaciones por síndrome urémico hemolítico en niños de 0 a 14 años en el Perú, periodo 2015 a 2022
(Universidad Nacional Mayor de San Marcos, Facultad de Medicina Humana, 2023)
Gemcitabine-related Thrombotic Microangiopathy: A Single-centre Retrospective Series
(Maney Publishing, 2014)
Baseline characteristics and evolution of Brazilian patients with atypical hemolytic uremic syndrome: first report of the Brazilian aHUS Registry
(Oxford Univ Press, 2022-04-11)
Background Atypical hemolytic uremic syndrome (aHUS) is an ultra-rare disease. Therefore, studies involving large samples are scarce, making registries powerful tools to evaluate cases. We present herein the first analysis ...