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Biological and structural characteristics of the binding peptides from the sporozoite proteins essential for cell traversal (SPECT)-1 and -2
The sporozoite microneme proteins essential for cell traversal, SPECT-1 and SPECT-2, are considered attractive pre-erythrocytic immune targets due to the key role they play in crossing of the malaria parasite across the ...
Shortening and modifying the 1513 MSP-1 peptide’s ?-helical region induces protection against malaria
Immunogenic and protective peptide sequences are of prime importance in the search for an anti-malarial vaccine. The MSP-1 conserved and semi-conserved sequences have been shown to contain red blood cell (RBC) membrane ...
Estudios de estabilidad de la proteína Bax humana
(2012-01-10)
Bax is a member of the Bcl-2 protein family that participates in mitochondrionmediated
apoptosis. In the early stages of the apoptotic pathway, Bax migrates from
the cytosol to the outer mitochondrial membrane, where it ...
Topography of nicotinic acetylcholine receptor membrane-embedded domains
(American Society for Biochemistry and Molecular Biology, 2000-12)
The topography of nicotinic acetylcholine receptor (AChR) membrane-embedded domains and the relative affinity of lipids for these protein regions were studied using fluorescence methods. Intact Torpedo californica AChR ...
C-terminal Lysine-Linked Magainin 2 with Increased Activity Against Multidrug-Resistant Bacteria
(Bentham Science Publ Ltd, 2016-01-01)
Due to the growing problem of antibiotic-resistant microorganisms, the development of novel antimicrobial agents is a very important challenge. Dimerization of cationic antimicrobial peptides (cAMPs) is a potential strategy ...
C-terminal lysine-linked magainin 2 with increased activity against multidrug-resistant bacteria
(2016-08-01)
Due to the growing problem of antibiotic-resistant microorganisms, the development of novel antimicrobial agents is a very important challenge. Dimerization of cationic antimicrobial peptides (cAMPs) is a potential strategy ...
N-Terminal microdomain peptide from human dihydroorotate dehydrogenase: structure and model membrane interactions
(2014)
The N-terminus of the human dihydroorotate dehydrogenase (HsDHODH) has been described as important for the enzyme attachment in the inner mitochondrial membrane and possibly to regulate enzymatic activity. In this study, ...
Brij Detergents Reveal New Aspects Of Membrane Microdomain In Erythrocytes
(Informa Healthcare, 2014)
Activation of the bacterial thermosensor DesK involves a serine zipper dimerization motif that is modulated by bilayer thickness
(National Academy of Sciences, 2015-05)
DesK is a bacterial thermosensor protein involved in maintaining membrane fluidity in response to changes in environmental temperature. Most likely, the protein is activated by changes in membrane thickness, but the molecular ...
Not all ALMT1-type transporters mediate aluminum-activated organic acid responses: the case of ZmALMT1 - an anion-selective transporter
(Blackwell PublishingOxfordInglaterra, 2008)