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Efecto de la aplicación de dexametasona en la evolución de la enfermedad hepática crónica, en un modelo de experimentación murinoEffect of the application of dexamethasone on the evolution of the chronic liver disease, in a murine experimental modelEfeito da aplicação de dexametasona na evolução da doença hepática crônica, num modelo de experimentação murino
(Corporación Universitaria Lasallista, 2012)
The role of transforming growth factor (TGF)-β in modulating the immune response and fibrogenesis in the gut
(Elsevier, 2014-02)
Transforming growth factor (TGF)-b, a pleiotropic cytokine released by both immune and non-immune cells in the gut, exerts an important tolerogenic action by promoting regulatory T cell differentiation. TGF-balso enhances ...
Capillaria hepatica-induced septal fibrosis in rats: a contribution to the study of liver fibrogenesis
(Sociedade Brasileira de Medicina Tropical, 2010)
INTRODUÇÃO: A fibrose septal do fígado se desenvolve regularmente em ratos infectados pelo nematódeo Capillaria hepatica. O tratamento curativo da infecção, feito antes do 15º dia da infecção, mas não mais tarde, impediu ...
Immunohistochemical studies of stellate cells in experimental cholestasis in newborn and adult rats
(Faculdade de Medicina / USP, 2008)
BACKGROUND AND AIMS: Although there is much known about liver diseases, some aspects remain unclear, such as the nature of the differences between the diseases observed in newborn infants and those in adults. For example, ...
Altered global microRNA expression in hepatic stellate cells LX-2 by angiotensin-(1–7) and miRNA-1914-5p identification as regulator of pro-fibrogenic elements and lipid metabolism
(2018-05-01)
The development of new therapeutic strategies to control or reverse hepatic fibrosis requires thorough knowledge about its molecular and cellular basis. It is known that the heptapeptide angiotensin-(1–7) [ang-(1–7)] can ...
Effect of a thrombin receptor (protease-activated receptor 1, PAR-1) gene polymorphism in chronic hepatitis C liver fibrosis
(WILEY-BLACKWELL, 2008)
Background and Aim: Tissue injury leads to activation of coagulation and generation of thrombin. Inhibition of thrombin receptor protease-activated receptor 1 (PAR-1) has been shown to reduce liver fibrosis in animals. ...
Foetal development of skeletal muscle in bovines as a function of maternal nutrition, foetal sex and gestational age
(Journal of Animal Physiology and Animal Nutrition, 2018)
Losartan modulation on NOS isoforms and COX-2 expression in early renal fibrogenesis in unilateral obstruction
(Elsevier, 2004-12)
BACKGROUND: Angiotensin II plays a central role in the initiation of renal fibrogenesis at a very early stage leading to a rapid progression in unilateral ureteral obstruction (UUO). We examined the effect of an angiotensin ...