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Lack of association between BRAF mutation and MAPK ERK activation in melanocytic nevi
(NATURE PUBLISHING GROUP, 2006)
The mitogen-activated protein kinase (MAPK) extracellular signal-regulated kinase signaling pathway can be activated through mutations of V-RAF murine sarcoma viral oncogene homolog B1 (BRAF) oncogene, frequently found in ...
Activation of protein tyrosine kinase: A possible requirement for fixed-bacteria and lipopolysaccharide-induced increase in human natural killer cell activity
(1996)
Preincubation of peripheral blood lymphocytes (PBL) from drug-free, healthy volunteers with either the protein tyrosine kinase inhibitor genistein (GNT, n = 10, final concentration 200 μM) or the protein kinase A activator ...
A protein kinase screen of Neurospora crassa mutant strains reveals that the SNF1 protein kinase promotes glycogen synthase phosphorylation
(2014)
Glycogen functions as a carbohydrate reserve in a variety of organisms and its metabolism is highly regulated. The activities of glycogen synthase and glycogen phosphorylase, the rate-limiting enzymes of the synthesis and ...
Autophosphorylation of carboxy-terminal residues inhibits the activity of protein kinase CK1α
(2009)
CK1 constitutes a protein kinase subfamily that is involved in many important physiological processes. However, there is limited knowledge about mechanisms that regulate their activity. Isoforms CK1δ and CKlε were previously ...
Effects of PKCα activation on Ca2+ pump and K(Ca) channel in deoxygenated sickle cells
(1997)
We have previously shown that a pretreatment with phorbol 12-myristate 13-acetate (PMA), an activator of protein kinase C (PKC), reduced deoxygenation-induced K+ loss and Ca2+ uptake and prevented call dehydration in sickle ...
Divalent cation hinder the solubilization of a tubulin kinase activity from Trypanosoma cruzi epimastigotes
(Sociedad de Biología de Chile, 2003)