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Princípios básicos e aplicação da iontoforese na penetração cutânea de fármacos
(Sociedade Brasileira de Química, 2008)
Physicochemical constraints severely limit the number of molecules that can be considered as candidates for transdermal delivery. Iontophoresis is a non-invasive technique in which a weak electric current is used to enhance ...
Surfactant-based transdermal system for fluconazole skin delivery
(2014)
The development of a controlled-release dosage form of antifungals is of crucial importance in view of the side-effects of conventional oral and intravenous treatments of Sporotrichosis. In this study, systems composed of ...
Comparative bioavailability study of two 100-mu g daily 17-beta-estradiol transdermal delivery systems: Once-a-week matrix patch and twice-a-week reservoir patch in healthy postmenopausal women
(Excerpta Medica Inc, 1999-03-01)
An open-label, randomized, a-period, crossover study was conducted in healthy postmenopausal women to assess the relative bioavailability of 17-beta-estradiol from a new matrix system versus a standard reservoir transdermal ...
Comparative bioavailability study of an once-a-week matrix versus a twice-a-week reservoir transdermal estradiol delivery systems in postmenopausal women
(Elsevier B.V., 1996-04-01)
An open-label, randomised, crossover study was conducted with in healthy postmenopausal women to compare the relative bioavailability of a matrix transdermal estradiol delivery system worn for 7 consecutive days, versus a ...
Transdermal Glyceryl Trinitrate as an Effective Adjunctive Treatment with Artemether for Late-Stage Experimental Cerebral Malaria
(American Society for Microbiology, 2016)
Carbon nanotubes buckypapers for potential transdermal drug delivery
(Elsevier Science, 2015-07)
Drug loaded buckypapers based on different types of carbon nanotubes (CNTs) were prepared and characterized in order to evaluate their potentialities for the design of novel transdermal drug delivery systems. Lab-synthesized ...
Development and in vitro evaluation of potential electromodulated transdermal drug delivery systems based on carbon nanotube buckypapers
(Elsevier Science, 2017-07)
Buckypapers based on different types of carbon nanotubes with and without the addition of four model drugs, two of basic nature (clonidine hydrochloride, selegiline hydrochloride) and the others of acidic character ...
Risedronate transdermal delivery system based on a fumaric copolymer for therapy of osteoporosis
(Elsevier Science, 2017-07)
Transdermal drug delivery system (TDDS) could be seen as alternative to the oral administration which avoids several adverse effects. In this study a novel TDDS for risedronate (RI), a bisphosphonate used for osteoporosis ...