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RNA interference-mediated knockdown of CD49e (alpha 5 integrin chain) in human thymic epithelial cells modulates the expression of multiple genes and decreases thymocyte adhesion
(BIOMED CENTRAL LTD, 2010)
Background: The thymus is a central lymphoid organ, in which bone marrow-derived T cell precursors undergo a complex process of maturation. Developing thymocytes interact with thymic microenvironment in a defined spatial ...
RNA interference-mediated knockdown of CD49e (α5 integrin chain) in human thymic epithelial cells modulates the expression of multiple genes and decreases thymocyte adhesion
(2010-12)
Abstract
Background
The thymus is a central lymphoid organ, in which bone marrow-derived T cell precursors undergo a complex process of maturation. Developing thymocytes interact with thymic microenvironment in ...
Severe Changes In Thymic Microenvironment In A Chronic Experimental Model Of Paracoccidioidomycosis
(Public Library ScienceSan Francisco, 2016)
Tuberculosis, the disrupted immune-endocrine response and the potential thymic repercussion as a contributing factor to disease physiopathology
(Frontiers Research Foundation, 2018-05)
Upon the pathogen encounter, the host seeks to ensure an adequate inflammatory reaction to combat infection but at the same time tries to prevent collateral damage, through several regulatory mechanisms, like an endocrine ...
Is the thymus a target organ in infectious diseases?
(Fundação Oswaldo Cruz. Instituto Oswaldo Cruz, 2019)