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Lipophilicity as a determinant of binding of procaine analogs to rat alpha(3)beta(4) nicotinic acetylcholine receptor
(WILEY-BLACKWELLHOBOKEN, 2012)
Nicotinic acetylcholine receptors (nAChRs) have been studied in detail with regard to their interaction with therapeutic and drug addiction-related compounds. Using a structureactivity approach, we have examined the ...
Toxicidade de fármacos nitrofurânicos
(2008-12-01)
During the structural designing of new drugs, it is possible predict the influence of specific chemical groups on pharmacological activity. Among these, the nitro group has potential antiparasitic activity, being present ...
Toxicidade de fármacos nitrofurânicos
(2008-12-01)
During the structural designing of new drugs, it is possible predict the influence of specific chemical groups on pharmacological activity. Among these, the nitro group has potential antiparasitic activity, being present ...
Limitaciones del valor DeltaV para la diferenciación del ambiente químico molecular
(Universidad Nacional de Colombia, Facultad de Ciencias, Departamento de QuímicaAnálisis de ResiduosBogotá, Colombia, 2022)
Quantitative structure-activity studies on a series of migrastatin analogs as inhibitors of cancer cell metastasis
(BENTHAM SCIENCE PUBL LTD, 2011)
Migrastatin, a macrolide natural product, and its structurally related analogs are potent inhibitors of cancer cell metastasis, invasion and migration. In the present work, a specialized fragment-based method was employed ...
Validation of microbiological assay for determination of cefuroxime in injectable preparations
(2012-08-22)
The validation of a microbiological assay, applying agar diffusion method for determination of the active of cefuroxime in power for injection, is described. Using a strain of Micrococcus luteus ATCC 9341 as the test ...
Validation of microbiological assay for determination of cefuroxime in injectable preparations
(2012-08-22)
The validation of a microbiological assay, applying agar diffusion method for determination of the active of cefuroxime in power for injection, is described. Using a strain of Micrococcus luteus ATCC 9341 as the test ...