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The role of the de novo pyrimidine biosynthetic pathway in Cryptococcus neoformans high temperature growth and virulence
(Elsevier B.V., 2014-09-01)
Fungal infections are often difficult to treat due to the inherent similarities between fungal and animal cells and the resulting host toxicity from many antifungal compounds. Cryptococcus neoformans is an opportunistic ...
A Pyrimidine-â-carboline and Other Alkaloids from Annona foetida with Antileishmanial Activity
(American Chemical Society, 2020)
Estudo de reações de N-alquilação de pirimidin-2-onas: síntese de novos análogos nucleosídicos modificados
(Universidade Federal de Santa MariaBRQuímicaUFSMPrograma de Pós-Graduação em Química, 2008-01-15)
This work presents a study of the N-alkylation reactions of 4-
(trichloromethyl)pyrimidin-2(1H)-one(2), 5-bromo-4-methoxy-4-(trichloromethyl)-3,4-dihydropyrimidin-2-(1H)-one (7), 4-methoxy-4-(trichloromethyl)-3,4-dihydr ...
Pyrazolo[1,5a]pyrimidines as a new class of FUSE binding protein 1 (FUBP1) inhibitors
(Pergamon-Elsevier Science Ltd, 2016-11)
The transcriptional regulator FUSE binding protein 1 (FUBP1) is aberrantly upregulated in various malignancies, fulfilling its oncogenic role by the deregulation of critical genes involved in cell cycle control and apoptosis ...
Gas Chromatographic Determination of Cyprodinil, Fludioxonil, Pyrimethanil, and Tebuconazole in Grapes, Must, and Wine
(1997-07-01)
A rapid and simple gas chromatographic method for determinating cyprodinil, fludioxonil, pyrimethanil, and tebuconazole in grapes, must, and wine is described. An on-line microextraction method was used with a one-step ...
Gas Chromatographic Determination of Cyprodinil, Fludioxonil, Pyrimethanil, and Tebuconazole in Grapes, Must, and Wine
(1997-07-01)
A rapid and simple gas chromatographic method for determinating cyprodinil, fludioxonil, pyrimethanil, and tebuconazole in grapes, must, and wine is described. An on-line microextraction method was used with a one-step ...