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Single step recombinant human growth hormone (rhGH) purification from milk by peptide affinity chromatography
(American Chemical Society, 2018-07)
Recombinant human growth hormone (rhGH) is used for the treatment of several pathologies, most of them related to growth. Although different expression systems can be used for its production, the milk from transgenic cows ...
A liver metalloendopeptidase which degrades the circulating hypotensive peptide hormones bradykinin and atrial natriuretic peptide
(Associação Brasileira de Divulgação Científica, 1999-01-01)
A new metalloendopeptidase was purified to apparent homogeneity from a homogenate of normal human liver using successive steps of chromatography on DEAE-cellulose, hydroxyapatite and Sephacryl S-200. The purified enzyme ...
Growth factors and hormones pro-peptides: the unexpected adventures of the BDNF prodomain
(Wiley Blackwell Publishing, Inc, 2017-05)
Most growth factors and hormones are synthesized as pre-pro-proteins which are processed to the biologically active mature protein. The pre- and prodomains are cleaved from the precursor protein in the secretory pathway ...
Diagnosis of 5α-reductase type 2 deficiency: Contribution of anti-Müllerian hormone evaluation
(2005-12-01)
Aim: To evaluate anti-Müllerian hormone (AMH) levels in patients with clinical and molecular diagnosis of 5α-reductase 2 deficiency. Patients and methods: Data from 14 patients whose age ranged from 21 days to 29 years ...
Diagnosis of 5α-reductase type 2 deficiency: Contribution of anti-Müllerian hormone evaluation
(2005-12-01)
Aim: To evaluate anti-Müllerian hormone (AMH) levels in patients with clinical and molecular diagnosis of 5α-reductase 2 deficiency. Patients and methods: Data from 14 patients whose age ranged from 21 days to 29 years ...
Steroid hormones interact with natriuretic peptide C to delay nuclear maturation, to maintain oocyte-cumulus communication and to improve the quality of in vitro-produced embryos in cattle
(Csiro Publishing, 2017-10-01)
In vivo, oocyte maturation is triggered by the ovulatory LH surge, whereas in vitro it is precociously induced when the cumulus-oocyte complex is removed from the follicle. Natriuretic peptide C (NPPC) delays germinal ...
Orcokinins regulate the expression of neuropeptide precursor genes related to ecdysis in the hemimetabolous insect Rhodnius prolixus
(Pergamon-Elsevier Science Ltd, 2018-07)
Ecdysis is a vital process for insects, during which they shed the old cuticle in order to emerge as the following developmental stage. Given its relevance for survival and reproduction, ecdysis is tightly regulated by ...