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Gender does not influence neuromuscular properties in dimorphic skeletal muscles of the toad
(Elsevier B.V., 1998-10-01)
The aim of this work was to study gender differences on the physiology of the dimorphic brachial musculature involved in the clasp reflex of the toad (Bufo marinus L.). the neuromuscular transmission, the sensitivity to ...
Mechanism of calcium potentiation of the α7 nicotinic acetylcholine receptor
(Rockefeller University Press, 2020-07-23)
The α7 nicotinic acetylcholine receptor (nAChR) is among the most abundant types of nAChR in the brain, yet the ability of nerve-released ACh to activate α7 remains enigmatic. In particular, a major population of α7 resides ...
Allosteric modulation of α7 nicotinic receptors by flavonoids
(SAGE Publications, 2018)
Plants have emerged as a valuable source for neuroprotective compounds like flavonoids. These polyphenolic com pounds decrease neurotoxicity and the development of neurodegeneration. Potentiation of α7 nicotinic receptor, ...
Estudo da atividade bloqueadora de N-Alquilbenzenossulfonamidas em canais iônicos, com enfase em canais para potássio
(Universidade Estadual Paulista (Unesp), 2016-06-23)
Esta tese teve como objetivo estudar as moléculas orgânicas (N-alquilbenzenossulfonamidas) como inibidoras de canais para potássio do tipo KV3.1, heterologamente expressos em células L-929. Com o presente estudo constatou-se ...