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Mesenchymal stromal cells engineered to produce IGF-I by recombinant adenovirus ameliorate liver fibrosis in mice
(Mary Ann Liebert, 2014-12)
Liver cirrhosis involves chronic wound healing and fibrotic processes. Mesenchymal stromal cells (MSCs) are multipotent adult progenitor cells that are used as vehicles of therapeutic genes. Insulin growth factor like-I ...
Geração de células semelhantes a hepatócitos por reprogramação direta de células-tronco mesenquimais
(Instituto Gonçalo Moniz, 2019)
Caracterização de célula progenitora hepática no cultivo celular de fígado de feto canino
(Universidade Estadual Paulista (Unesp), 2016-02-25)
Resumo - Com a descoberta das células-tronco abriu-se um leque de possibilidades nas pesquisas de nichos destas em diferentes órgãos e também no estudo de doenças e regeneração tecidual. O fígado vem sendo alvo de muitos ...
Vacinação de Hepatite A em receptores de células tronco hematopoiéticas (TCTH)Hepatitis A vaccination in hematopoietic stem cell receptors (HSCT)
(Universidade Estadual Paulista (Unesp), 2016)
Intravenous administration of multipotent stromal cells prevents the onset of non-alcoholic steatohepatitis in obese mice with metabolic syndrome
(2011)
Background & Aims: Metabolic syndrome is secondary to obesity and characterized by dyslipidemia, insulin resistance, and hypertension. Non-alcoholic fatty liver disease is its hepatic manifestation, whose progression-limiting ...
Intravenous administration of multipotent stromal cells prevents the onset of non-alcoholic steatohepatitis in obese mice with metabolic syndrome
(2011)
Background & Aims: Metabolic syndrome is secondary to obesity and characterized by dyslipidemia, insulin resistance, and hypertension. Non-alcoholic fatty liver disease is its hepatic manifestation, whose progression-limiting ...
Infusion of autologous bone marrow mononuclear cells through hepatic artery results in a short-term improvement of liver function in patients with chronic liver disease: a pilot randomized controlled study
(2010)
Aim: This randomized controlled study evaluated the effect of autologous infusion of bone marrow cells (BMC) in patients with hepatic cirrhosis.
Methods: Thirty patients on the liver transplant waiting list were randomly ...