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Crosstalk between tumor-infiltrating immune cells and cancer-associated Fibroblasts in tumor growth and immunosuppression of breast cancer
(Hindawi, 2021)
Signals from the tumor microenvironment (TME) have a profound influence on the maintenance and progression of cancers.
Chronic inflammation and the infiltration of immune cells in breast cancer (BC) have been strongly ...
Thyroid status regulates the tumor microenvironment delineating breast cancer fate
(Society for Endocrinology, 2022)
Shaping the Immune Landscape in Cancer by Galectin-Driven Regulatory Pathways
(Elsevier, 2016-03-30)
Along with the discovery of tumor-driven inflammatory pathways, there has been a considerable progress over the past 10 years in understanding the mechanisms leading to cancer immunosurveillance and immunoediting. Several ...
Chronic Hepatitis C Pathogenesis: Immune Response in the Liver Microenvironment and Peripheral Compartment
(Frontiers Media, 2021-08)
Chronic hepatitis C (CHC) pathogenic mechanisms as well as the participation of the immune response in the generation of liver damage are still a topic of interest. Here, we evaluated immune cell populations and cytokines ...
T regulatory cells-derived extracellular vesicles and their contribution to the generation of immune tolerance
(Wiley, 2020)
T regulatory (Treg) cells have a major role in the maintenance of immune tolerance against self and foreign antigens through the control of harmful inflammation. Treg cells exert immunosuppressive function by several ...
Thyroid status regulates the tumor microenvironment delineating breast cancer fate
(BioScientifica, 2021-07)
The patient’s hormonal context plays a crucial role in the outcome of cancer. However, the association between thyroid disease and breast cancer risk remains unclear. We evaluated the effect of thyroid status on breast ...
The Antidiabetic Effect of Mesenchymal Stem Cells Is Unrelated to Their Transdifferentiation Potential But to Their Capability to Restore Th1/Th2 Balance and to Modify the Pancreatic Microenvironment
(2012)
Type 1 diabetes mellitus (T1DM) is a chronic metabolic disease that results from cell-mediated autoimmune destruction of insulin-producing cells. In T1DM animal models, it has been shown that the systemic administration ...