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Interaction of acylated and substituted antimicrobial peptide analogs with phospholipid-polydiacetylene vesicles. Correlation with their biological properties
(Wiley Blackwell Publishing, Inc, 2011-07)
A series of peptide analogs based on region 6-22 of Plantaricin 149 sequence were synthesized. The interaction between these analogs and phospholipid-polydiacetylene vesicles was investigated to evaluate the ability of the ...
Immunogenicity and protectivity of Plasmodium falciparum EBA-175 peptide and its analog is associated with alpha-helical region shortening and displacement
EBA-175 protein is used as a ligand in the binding of P. falciparum to red blood cells (RBCs). Evidence shows that the conserved peptide 1779 from this protein (with high red blood cell binding ability and known critical ...
CONFORMATION of ANGIOTENSIN-II in AQUEOUS-SOLUTION - TITRATION of SEVERAL PEPTIDE ANALOGS and HOMOLOGS
(Amer Chemical Soc, 1974-01-01)
Membrane targeting peptides toward antileishmanial activity: Design, structural determination and mechanism of interaction
(Elsevier B.V., 2017-11-01)
Background: Leishmaniasis threatens poor areas population worldwide, requiring new drugs less prone to resistance development. Antimicrobial peptides with antileishmanial activity are considered among fulfilling alternatives, ...
Chemical and Biological Characteristics of Antimicrobial alpha-Helical Peptides Found in Solitary Wasp Venoms and Their Interactions with Model Membranes
(Mdpi, 2019-10-01)
Solitary wasps use their stinging venoms for paralyzing insect or spider prey and feeding them to their larvae. We have surveyed bioactive substances in solitary wasp venoms, and found antimicrobial peptides together with ...
Antifungal Activity, Toxicity, and Membranolytic Action of a Mastoparan Analog Peptide
(2019-12-06)
Invasive fungal infections, such as cryptococcosis and paracoccidioidomycosis are associated with significant rates of morbidity and mortality. Cryptococcosis, caused by Cryptococcus neoformans, is distributed worldwide ...
Effects of Dimerization on the Structure and Biological Activity of Antimicrobial Peptide Ctx-Ha
(Amer Soc Microbiology, 2012-06-01)
It is well known that cationic antimicrobial peptides (cAMPs) are potential microbicidal agents for the increasing problem of antimicrobial resistance. However, the physicochemical properties of each peptide need to be ...
Effects of Dimerization on the Structure and Biological Activity of Antimicrobial Peptide Ctx-Ha
(Amer Soc Microbiology, 2012-06-01)
It is well known that cationic antimicrobial peptides (cAMPs) are potential microbicidal agents for the increasing problem of antimicrobial resistance. However, the physicochemical properties of each peptide need to be ...
A study of the anti-plasmodium activity of angiotensin II analogs
(John Wiley & SonsChichester, 2013-09)
Controlling the dissemination of malaria requires the development of new drugs against its etiological agent, a protozoan of the Plasmodium genus. Angiotensin II and its analog peptides exhibit activity against the development ...