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Calcium, iron and neuronal function
(2007)
Calcium and iron play dual roles in neuronal function: they are both essential but when present in excess they cause neuronal damage and may even induce neuronal death. Calcium signals are required for synaptic plasticity, ...
Rapid signaling of strogen to neuronal dendrite spine formation
(Lambert Academic Publishing, 2012)
Estrogens are important regulators of neuronal cell morphology and this is thought to be critical for gender-specific differences in brain function and dysfunction. Dendritic spine formation is dependent on actin remodeling ...
Specification of excitatory neurons in the developing cerebral cortex: progenitor diversity and environmental influences
(2015-01-12)
The mature cerebral cortex harbors a heterogeneous population of glutamatergic neurons,
organized into a highly intricate histological architecture. Classically, this mixed population
of neurons was thought to be generated ...
Effect of Alcohol on Hippocampal-Dependent Plasticity and Behavior: Role of Glutamatergic Synaptic Transmission
(Frontiers Media S.A., 2020)
Decrease of Rab11 prevents the correct dendritic arborization, synaptic plasticity and spatial memory formation
(Elsevier Science, 2020-09)
Emerging evidence shows that Rab11 recycling endosomes (REs Rab11) are essential for several neuronal processes, including the proper functioning of growth cones, synapse architecture regulation and neuronal migration. ...
Circadian pacemaker neurons change synaptic contacts across the day
(Elsevier, 2014-08)
Daily cycles of rest and activity are a common example of circadian control of physiology. In Drosophila, rhythmic locomotor cycles rely on the activity of 150-200 neurons grouped in seven clusters [1, 2]. Work from many ...
The membrane glycoprotein M6a endocytic/recycling pathway involves clathrin-mediated endocytosis and affects neuronal synapses
(Frontiers Editorial Office, 2017-09)
Single point mutations or variations in the expression of the gene encoding theneuronal glycoprotein M6a have been associated with psychiatric disorders such as Alzheimer, depression and schizophrenia. In cultured neurons, ...
Requirement of Adult-Born Neurons for Hippocampus-Dependent Learning
(Elsevier Science, 2012-02)
A fundamental question in the field of adult neurogenesis relies in addressing whether neurons generated in the adult dentate gyrus are needed for hippocampal function. Increasing evidence is accumulating in support of the ...