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Machine learning reveals a non‐canonical mode of peptide binding to MHC class II molecules
(Wiley Blackwell Publishing, Inc, 2017-10)
MHC class II molecules play a fundamental role in the cellular immune system: they load short peptide fragments derived from extracellular proteins and present them on the cell surface. It is currently thought that the ...
Bacterial RNA Contributes to the Down-Modulation of MHC-II Expression on Monocytes/Macrophages Diminishing CD4+ T Cell Responses
(Frontiers, 2019-09)
Brucella abortus, the causative agent of brucellosis, displays many resources to evade T cell responses conducive to persist inside the host. Our laboratory has previously showed that infection of human monocytes with B. ...
Distribución de alelos HLA de clase y clase I y II en la población peruana
(Seguro Social de Salud (EsSalud), 2000-12)
La distribución de los alelos HLA – A -B -C DRB1 y DQB1 en la población peruana fue estudiada y comparada con aquellos alelos de otras poblaciones para proporcionar información extensa acerca del origen antropológico en ...
Chlamydia trachomatis Infection Impairs MHC-I Intracellular Trafficking and Antigen Cross-Presentation by Dendritic Cells
(Frontiers Media, 2021-04)
During cross-presentation, exogenous antigens (i.e. intracellular pathogens or tumor cells) are internalized and processed within the endocytic system and also by the proteasome in the cytosol. Then, antigenic peptides are ...
Increased susceptibility to Strongyloides venezuelensis infection is related to the parasite load and absence of major histocompatibility complex (MHC) class II molecules
(Academic Press Inc Elsevier ScienceSan DiegoEUA, 2013)
Imunolocalização e alterações patológicas induzidas pela infecção por Strongyloides venezuelensis em camundongos geneticamente deficientes em MHC de classe I ou II
(Universidade Federal de UberlândiaBRPrograma de Pós-graduação em Imunologia e Parasitologia AplicadasCiências BiológicasUFU, 2016)
Immunolocalization and pathological alterations following Strongyloides venezuelensis infection in the lungs and the intestine of MHC class I or II deficient mice
(ELSEVIER SCIENCE BV, 2008)
The present study, investigated the mechanisms involved in the immune responses of Major Histocompatibility Complex class I or class II knockout mice, following Strongyloides venezuelensis infection. Wild-type C57BL/6 (WT), ...