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Aplicaciones médicas de las células pluripotentes inducidas paciente-específicas
(Universidad Militar Nueva Granada, 2013)
Aplicaciones médicas de las células pluripotentes inducidas paciente-específicas
(Universidad Militar Nueva Granada, 2013)
Deep Learning Neural Networks Highly Predict Very Early Onset of Pluripotent Stem Cell Differentiation
(Cell Press, 2019-04-09)
Deep learning is a significant step forward for developing autonomous tasks. One of its branches, computer vision, allows image recognition with high accuracy thanks to the use of convolutional neural networks (CNNs). Our ...
Reprogramming of prostate cancer-associated stromal cells to embryonic stem-like
(WILEY-BLACKWELLHOBOKEN, 2012)
BACKGROUND CD90+ prostate cancer-associated (CP) stromal cells represent a diseased cell type found only in tumor tissue. They differ from their normal counterpart in gene expression and inductive signaling. Genetic ...
Dynamical reorganization of the pluripotency transcription factors Oct4 and Sox2 during early differentiation of embryonic stem cells
(Nature, 2020-03)
Pluripotency maintenance requires transcription factors (TFs) that induce genes necessary to preserve the undifferentiated state and repress others involved in differentiation. Recent observations support that the heterogeneous ...
IPSCs: A Minireview from bench to bed, including organoids and the crispr system
(Hindawi Publishing Corporation, 2016-01)
When Dolly the sheep was born, the first probe into an adult mammalian genome traveling back in time and generating a whole new animal appeared. Ten years later, the reprogramming process became a defined method of producing ...
Generation and genetic repair of two human induced pluripotent cell lines from patients with Epidermolysis Bullosa simplex and dilated cardiomyopathy associated with a heterozygous mutation in the translation initiation codon of KLHL24
(2021)
Fibroblasts from two patients carrying a heterozygous mutation in the translation initiation codon (c.2 T > G) of the kelch-like protein 24 (KLHL24) gene were used to
generate human induced pluripotent stem cells (hiPSCs), ...
Agathisflavone Enhances Retinoic Acid-Induced Neurogenesis and Its Receptors α and β in Pluripotent Stem Cells
(2011)
Flavonoids have key functions in the regulation of multiple cellular processes; however, their effects have been poorly examined in pluripotent stem cells. Here, we tested the hypothesis that neurogenesis induced by all-trans ...