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Commentary: Arginine vasopressin receptor 1a is a therapeutic target for castration-resistant prostate cancer
(Frontiers Media, 2020-01-10)
Prostate cancer patients managed with androgen-deprivation therapy usually recur after a few years and the disease gradually becomes castration-resistant prostate cancer (CRPC). The role of tumor cell plasticity, including ...
Diabetes insípido em paciente com esclerose múltipla
(Sociedade Brasileira de Endocrinologia e Metabologia, 2008-02-01)
Multiple Sclerosis (ME) is a chronic progressive disease characterized by relapses of demyelination that can occur anywhere in the brain stem, spinal cord and optic nerve. Since central diabetes insipidus (DI) is mainly ...
Von Willebrand's disease diagnosis and laboratory issues
(Wiley Blackwell Publishing, Inc, 2010-07)
In this paper, the recent developments in the diagnosis and laboratory issues of von Willebrand's disease (VWD) are presented. Dr. Castaman reviews the functional tests available for the diagnosis of VWD and their ...
Structure-activity relationship of 1-desamino-8-D-arginine vasopressin as an antiproliferative agent on human vasopressin V2 receptor-expressing cancer cells
(Spandidos Publications, 2014-04)
The synthetic nonapeptide 1-desamino-8-D-arginine vasopressin (dDAVP) can reduce tumor cell growth through agonist action on the vasopressin V2 receptor. A structure-antiproliferative activity relationship analysis of dDAVP ...
Desmopressin inhibits lung and lymph node metastasis in a mouse mammary carcinoma model of surgical manipulation
(Wiley-liss, Div John Wiley & Sons Inc, 2002-09)
Background and Objectives: Desmopressin (DDAVP) is a synthetic derivative of vasopressin with hemostatic and fibrinolytic properties that has been used during surgery in patients with bleeding disorders. Our aim was to ...
Reduction of tumor angiogenesis induced by desmopressin in a breast cancer model
(Springer, 2013-10)
Desmopressin (DDAVP), a synthetic peptide analog of vasopressin, is a safe antidiuretic and hemostatic compound that acts as a selective agonist for the vasopressin V2 membrane receptor. It is known that DDAVP can inhibit ...
Peri-operative biology in primary breast cancer: selective targeting of vasopressin type 2 receptor using desmopressin as a novel therapeutic approach
(Springer, 2016-06)
In breast cancer patients, surgical excision of the primary tumor is commonly the first step towards long-term control of disease progression. However, recent evidence suggests that surgery may also promote metastatic ...