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Cell therapy prevents structural, functional and molecular remodeling of remote non-infarcted myocardium
(Elsevier Ireland LtdClareIrlanda, 2013)
Influência do treinamento físico aeróbio no remodelamento cardíaco de ratos espontaneamente hipertensos tratados com Dexametasona
(Universidade Federal de São CarlosUFSCarPrograma Interinstitucional de Pós-Graduação em Ciências Fisiológicas - PIPGCFCâmpus São Carlos, 2019-02-22)
It has been shown that chronic treatment with dexamethasone (DEX) promotes cardiac remodeling and hypertension (H) in normotensive rats, however little is known about the effects of DEX in spontaneously hypertensive animals ...
Influence of intermittent fasting on myocardial infarction-induced cardiac remodeling
(2019-05-28)
Background: Information on the role of intermittent fasting (IF) on pathologic cardiac remodeling is scarce. We compared the effects of IF before and after myocardial infarction (MI) on rat cardiac remodeling and survival. ...
Efeitos do estresse pelo frio sobre o tamanho nuclear do cardiomiócito em ratos: avaliação por microscopia de luz
(Sociedade Brasileira de Cirurgia Cardiovascular, 2008-12-01)
INTRODUCTION: Total body induced hypothermia and myocardial cooling are effective methods regarding myocardial protection during heart surgery and ischemia. It is described in previous studies that extreme low temperature ...
Cardiomyocyte death: Mechanisms and translational implications
(2011)
Cardiovascular disease (CVD) is the leading cause of morbidity and mortality worldwide. Although treatments have improved, development of novel therapies for patients with CVD remains a major research goal. Apoptosis, ...
Endogenous osteopontin induces myocardial CCL5 and MMP-2 activation that contributes to inflammation and cardiac remodeling in a mouse model of chronic Chagas heart disease
(Elsevier Science, 2018-01)
Cardiac dysfunction with progressive inflammation and fibrosis is a hallmark of Chagas disease caused by persistent Trypanosoma cruzi infection. Osteopontin (OPN) is a pro-inflammatory cytokine that orchestrates mechanisms ...
Cardiac ischemic preconditioning prevents dystrophin proteolysis by MMP-2 inhibition
(Instituto de Histología y Embriología, 2016-09)
Dystrophin is a membrane-associated protein responsible for structural stability of the sarcolemma in cardiac myocytes and is very sensitive to ischemic damage. The goal of our study was to determine if ischemic preconditioning ...
Papel del factor de transcripción asociado a microftalmia en la patogénesis de la enfermedad cardiaca isquémica
(2014)
El factor de transcripción asociado a microftalmia (MITF) es una proteína de unión a DNA que regula la expresión de genes específicos. A nivel cardiaco no se conocen los cambios asociados con la disminución de su expresión ...