Buscar
Mostrando ítems 21-30 de 3040
LaTBP1: A Leishmania amazonensis DNA-binding protein that associates in vivo with telomeres and GT-rich DNA using a Myb-like domain
(Elsevier B.V., 2007-09-15)
Different species of Leishmania can cause a variety of medically important diseases, whose control and treatment are still health problems. Telomere binding proteins (TBPs) have potential as targets for anti-parasitic ...
Starch synthesis in ostreococcus tauri: The starch-binding domains of starch synthase III-B are essential for catalytic activity
(Frontiers Research Foundation, 2018-10)
Starch is the major energy storage carbohydrate in photosynthetic eukaryotes. Several enzymes are involved in building highly organized semi-crystalline starch granules, including starch-synthase III (SSIII), which is ...
Coupling of agonist binding to channel gating in an ACh-binding protein linked to an ion channel
(Nature Publishing Group, 2004-08-19)
Neurotransmitter receptors from the Cys-loop superfamily couple the binding of agonist to the opening of an intrinsic ion pore in the final step in rapid synaptic transmission. Although atomic resolution structural data ...
Side Fenestrations Provide an "anchor" for a Stable Binding of A1899 to the Pore of TASK-1 Potassium Channels
(American Chemical Society, 2017)
Polysaccharide-synthesizing Glycosyltransferases and Carbohydrate Binding Modules: the case of Starch Synthase III
(Bentham Science Publishers, 2013-05)
Glycosyltransferases (GTs) are a ubiquitous group of enzymes that catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. Nucleotide-sugars, lipid ...
Unravelling the interaction of piperlongumine with the nucleotide-binding domain of hsp70: A spectroscopic and in silico study
(2021-12-01)
Piperlongumine (PPL) is an alkaloid extracted from several pepper species that exhibits anti-inflammatory and anti-carcinogenic properties. Nevertheless, the molecular mode of action of PPL that confers such powerful ...
The Arabidopsis class I TCP transcription factor AtTCP11 is a developmental regulator with distinct DNA-binding properties due to the presence of a threonine residue at position 15 of the TCP domain
(Portland Press, 2011-04)
The TCP domain is a DNA-binding domain present in plant transcription factors that modulate different processes. In the present study, we show that Arabidopsis class I TCP proteins are able to interact with a dyad-symmetric ...
Distinctive Cognate Sequence Discrimination, Bound DNA Conformation, and Binding Modes in the E2 C-Terminal Domains from Prototype Human and Bovine Papillomaviruses
(American Chemical Society, 2000-11)
The C-terminal DNA binding domain of the E2 protein is involved in transcriptional regulation and DNA replication in papillomaviruses. At low ionic strength, the domain has a tendency to form aggregates, a process readily ...
A genetic and physical study of the interdomain linker of E-Coli AraC protein-a trans-subunit communication pathway
(Wiley, 2016)
Genetic experiments with full length AraC and biophysical experiments with its dimerization domain plus linker suggest that arabinose binding to the dimerization domain changes the properties of the inter-domain linker ...
Characterization of the functional domains of boar acrosin involved in nonenzymatic binding to homologous zona pellucida glycoproteins
(1998)
During the first steps of the gamete interaction, the proacrosin/acrosin system seems to play a crucial role in the secondary binding, holding acrosome-reacted spermatozoa during their passage through the zona pellucida. ...