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The Chromophore Structures of the Pr States in Plant and Bacterial Phytochromes
(Cell Press, 2007-10)
The resonance Raman spectra of the Pr state of the N-terminal 65-kDa fragment of plant phytochrome phyA have been measured and analyzed in terms of the configuration and conformation of the tetrapyrroles methine bridges. ...
Modulation of Antiviral Immunity by Heme Oxygenase-1
(2017)
Heme oxygenase-1 (H0-1) is a stress-inducible, anti-inflammatory, and cytoprotective enzyme expressed in most cell types in the organism. Under several stress stimuli, HO-1 expression and activity is up-regulated to catalyze ...
Multidimensional redox potential/pKacoupling in multicopper oxidases from molecular dynamics: implications for the proton transfer mechanism
(2021-12-28)
Bilirubin oxidases (BOD) are metalloenzymes that catalyze the conversion of O2and bilirubin to biliverdin and water in the metabolism of chlorophyll and porphyrin. In this work we have used the CpHMD method to analyze the ...
Heme oxygenase 1 overexpression increases iron fluxes in Caco-2 cells
(2006)
Heme oxygenase-1 is a microsomal enzyme that, when induced by stress, protects the cells from oxidative
injury. Heme oxygenase-1 participates in the cleavage of the heme ring producing biliverdin, CO and ferrous
Fe. The ...
Adaptive Potential of the Heme Oxygenase/Carbon Monoxide Pathway During Hypoxia
(Frontiers Media, 2020)
Heme oxygenase (HO) enzymes catalyze heme into biliverdin, releasing carbon monoxide (CO) and iron into circulation. These byproducts of heme degradation can have potent cytoprotective effects in the face of stressors such ...
Immunoregulatory Properties of Heme Oxygenase-1
(2011)
Heme oxygenase-1 (HO-1) is one of the three isoforms of the heme oxygenase enzyme that catabolyzes the degradation of heme into biliverdin with the production of free iron and CO. HO-1 is induced by its substrate and by ...
The Chromophore Structure of the Cyanobacterial Phytochrome Cph1 As Predicted by Time-Dependent Density Functional Theory
(AMER CHEMICAL SOC, 2008-12-25)
The UV-vis absorption spectra of the photoreceptor chromophores biliverdin (BV) in the ZZZssa conformation and the phycocyanobilin (PCB) with conformations ZZZssa and ZZZasa have been investigated by means of time-dependent ...
Role of locus coeruleus heme oxygenase-carbon monoxide-cGMP pathway during hypothermic response to restraint
(PERGAMON-ELSEVIER SCIENCE LTD, 2008)
Central heme oxigenase-carbon monoxide (HO-CO) pathway has been shown to play a pyretic role in the thermoregulatory response to restraint. However, the specific site in the central nervous system where CO may act modulating ...