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Preclinical therapy with vitamin d3 in experimental encephalomyelitis: Efficacy and comparison with paricalcitol
(2021-02-02)
Multiple sclerosis (MS) is a chronic demyelinating disease of the central nervous system (CNS). MS and its animal model called experimental autoimmune encephalomyelitis (EAE) immunopathogenesis involve a plethora of immune ...
Should mast cells be considered therapeutic targets in multiple sclerosis?
(2020-11-01)
Mast cells are immune cells of the myeloid lineage that are found throughout the body, including the central nervous system. They perform many functions associated with innate and specific immunity, angiogenesis, and ...
Opposing roles of interferon-gamma on cells of the central nervous system in autoimmune neuroinflammation
(Frontiers Media, 2015)
Multiple sclerosis (MS) is the principal cause of autoimmune neuroinflammation in humans, and its animal model, experimental autoimmune encephalomyelitis (EAE), is widely used to gain insight about their immunopathological ...
Pattern of cytokine secretion by peripheral blood cells of patients with multiple sclerosis in Brazil
(Nature Publishing GroupBasingstokeInglaterra, 2000)
Hypothalamic response to experimental allergic encephalomyelitis: Role of substance P
(KargerBaselSuíça, 2004)
Efficacy of the selective progesterone receptor agonist Nestorone for chronic experimental autoimmune encephalomyelitis
(Elsevier Inc, 2014-11-15)
Progesterone plays a protective role in the experimental autoimmune encephalomyelitis (EAE) model of multiple sclerosis (MS). Besides spinal cord neuropathology, MS patients present a dysfunctional hippocampus. In this ...
Glutamate Release Machinery Is Altered in the Frontal Cortex of Rats with Experimental Autoimmune Encephalomyelitis
(Springer, 2014-07)
Experimental autoimmune encephalomyelitis (EAE) is an animal model that mimics many of the clinical and pathological features of the human disease multiple sclerosis (MS). Both are inflammatory demyelinating and neurodegenerative ...
Interferon-beta modifies the peripheral blood cell cytokine secretion in patients with multiple sclerosis
(Elsevier Science BvAmsterdamHolanda, 2009)
Erythropoietin reduces experimental autoimmune encephalomyelitis severity via neuroprotective mechanisms
(BioMed Central, 2017)
BACKGROUND: Treatment with erythropoietin (Epo) in experimental autoimmune encephalomyelitis (EAE), the rodent model of multiple sclerosis (MS), has consistently been shown to ameliorate disease progression and improve ...
Nitric oxide and TNF alpha effects in experimental autoimmune encephalomyelitis demyelination
(KargerBaselSuíça, 2007)