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Modulation of inflammatory and hormonal parameters in response to testosterone therapy: Effects on the ventral prostate of adult rats
(Wiley-Blackwell, 2018-09-01)
Testosterone is often recommended in the treatment of several aging-related conditions. However, there are still questions about the consequences of this therapy in terms of hormonal and inflammatory parameters that are ...
Anabolic androgens restore mating after sexual satiety in male rats.
(Elsevier, 2008)
Obesity Impairs Leydig Cells Function in Adults Rats Due to Down Regulation of Androgen Receptor and 17 beta-HSD.
(Amer Soc Cell Biology, 2011-01-01)
Arrhythmogenic effect of androgens on the rat heart
(Springer Tokyo, 2017-01)
In most species androgens shorten the cardiac action potential and reduce the risk of afterdepolarizations. Despite the central role of the rat model in physiological studies, the effects of androgens on the rat heart are ...
Higher androgen bioactivity is associated with excessive erythrocytosis and chronic mountain sickness in Andean Highlanders: a review
(Wiley, 2015)
Populations living at high altitudes (HA), particularly in the Peruvian Central Andes, are characterised by presenting subjects with erythrocytosis and others with excessive erythrocytosis (EE)(Hb>21 g dl−1). EE is associated ...
Muscular atrophy, impaired epithelial autophagy and UCHL1 increase in androgen-deficient cauda epididymis
(2020-05-01)
In epididymis, cimetidine induces androgenic failure due to reduced sex hormone-binding globulin stromal levels and blockade of androgen receptor (AR) nuclear import. UCHL1, a hydrolase of ubiquitin-proteasome system (UPS), ...
Reduced levels of stromal sex hormone-binding globulin and androgen receptor dysfunction in the sperm storage region of the rat epididymis
(Bioscientifica Ltd, 2018-06-01)
The cauda epididymidis is the major sperm storage region whose androgenic supply, essential for the sperm viability, is provided by the vasculature and is dependent upon testosterone diffusion through the stromal tissue ...
The effects of testosterone on sleep and sleep-disordered breathing in men: Its bidirectional interaction with erectile function
(W B Saunders Co Ltd, 2008-10-01)
As a major androgen with a key rote in developing and maintaining mate sexual characteristics, testosterone exerts a broad range of actions regulating several systems throughout human life. This article reviews data on the ...