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AT2 Receptor Mediated Activation of the Tyrosine Phosphatase PTP1B Blocks Caveolin-1 Enhanced Migration, Invasion and Metastasis of Cancer Cells
(2019)
The renin-angiotensin receptor AT2R controls systemic blood pressure and is also suggested to modulate metastasis of cancer cells. However, in the latter case, the mechanisms involved downstream of AT2R remain to be defined. ...
Gold nanoparticles as tracking devices to shed light on the role of caveolin-1 in early stages of melanoma metastasis
(Future Medicine, 2018)
AIM
To track early events during lung metastasis, we labeled cells expressing (B16F10CAV1) or lacking CAV1 (B16F10mock) with gold nanoparticles conjugated to the peptide TAT (AuNPs-PEG-TAT).
METHODS
B16F10 expressing ...
Gold nanoparticles as tracking devices to shed light on the role of caveolin-1 in early stages of melanoma metastasis
(Future Medicine, 2018-06)
Aim: To track early events during lung metastasis, we labeled cells expressing (B16F10(CAV1)) or lacking CAV1 (B16F10(mock)) with gold nanoparticles conjugated to the peptide TAT (AuNPs-PEG-TAT). Methods: B16F10 expressing ...
Gold nanoparticles as tracking devices to shed light on the role of caveolin-1 in early stages of melanoma metastasis
(2018-06)
Aim: To track early events during lung metastasis, we labeled cells expressing (B16F10CAV1) or lacking CAV1 (B16F10mock) with gold nanoparticles conjugated to the peptide TAT (AuNPs-PEG-TAT). Methods: B16F10 expressing or ...
Extracellular matrix-specific Caveolin-1 phosphorylation on tyrosine 14 is linked to augmented melanoma metastasis but not tumorigenesis
(Impact Journals LLC, 2016)
Caveolin-1 (CAV1) is a scaffolding protein that plays a dual role in cancer. In advanced stages of this disease, CAV1 expression in tumor cells is associated with enhanced metastatic potential, while, at earlier stages, ...
Extracellular matrix-specific Caveolin-1 phosphorylation on tyrosine 14 is linked to augmented melanoma metastasis but not tumorigenesis
(2016)
Caveolin-1 (CAV1) is a scaffolding protein that plays a dual role in cancer. In advanced stages of this disease, CAV1 expression in tumor cells is associated with enhanced metastatic potential, while, at earlier stages, ...
Src-family kinase inhibitors block early steps of caveolin-1-enhanced lung metastasis by melanoma cells
(Elsevier, 2020)
In advanced stages of cancer disease, caveolin-1 (CAV1) expression increases and correlates with increased migratory and invasive capacity of the respective tumor cells. Previous findings from our laboratory revealed that ...
Src-family kinase inhibitors block early steps of caveolin-1-enhanced lungmetastasis by melanoma cells
(2020)
In advanced stages of cancer disease, caveolin-1 (CAV1) expression increases and correlates with increased migratory and invasive capacity of the respective tumor cells. Previous findings from our laboratory revealed that ...
Brucella abortus-Stimulated Platelets Activate Brain Microvascular Endothelial Cells Increasing Cell Transmigration through the Erk1/2 Pathway
(Multidisciplinary Digital Publishing Institute, 2020-08)
Central nervous system invasion by bacteria of the genus Brucella results in an inflammatory disorder called neurobrucellosis. A common feature associated with this pathology is blood–brain barrier (BBB) activation. However, ...