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Voltage-controlled gating in a large conductance Ca2+-sensitive K(+)channel (hslo)
(NATL ACAD SCIENCES, 1997-05-13)
Large conductance calcium- and voltage-sensitive K+ (MaxiK) channels share properties of voltage- and ligand-gated ion channels. In voltage-gated channels, membrane depolarization promotes the displacement of charged ...
Rational drug design targeting two-pore domian potassium channels TASK. Theoretical - Experimental approximation
(2014)
TASK-‐3
is
a
two-‐pore
domain
potassium
(K2P)
channel
highly
expressed
in
hippocampus,
cerebellum,
and
cortex.
TASK-‐3
regulates
neurotransmitter
functions
and
has
been
identified
as
an
oncogenic
potassium
channel
and ...
Study and discovery of TASK potassium channels modulators: A theoretical and experimental approach
(2016)
TASK-‐3
is
a
two-‐pore
domain
potassium
(K2P)
channel
highly
expressed
in
hippocampus,
cerebellum,
and
cortex.
TASK-‐3
regulates
neurotransmitter
functions
and
has
been
identified
as
an
oncogenic
potassium
channel
and ...
Muscarinic stimulation and pinacidil produce similar facilitation of tachyarrhythmia induction in rat isolated atria
(Academic Press Ltd- Elsevier Science LtdLondonInglaterra, 2013)
Rational design and biological activity of synthetic compounds as blockers of potassium channels TASK
(2017)
Potassium (K+) channels are part of one of the most abundant family of transmembrane proteins. K+ channels
allow the selective transfer of K+ ions inside or outside of the cell. Within this family we find K2P channels, ...
Nitric oxide activates a potassium current in olfactory receptor neurons from Caudiverbera caudiverbera and Xenopus laevis
(Elsevier, 1999)
The putative role of nitric oxide (NO) in the physiology of olfactory receptor neurons (ORNs) is controversial. Here we report that pulses of NO caused an outward current in voltage-clamped isolated olfactory neurons. The ...