Buscar
Mostrando ítems 11-20 de 657
Preliminary functional characterization, cloning and primary sequence of Fastuosain, a cysteine peptidase isolated from fruits of Bromelia fastuosa
(Bentham Science Publ Ltd, 2006-01-01)
The present work reports the characterization of Fastuosain, a novel cysteine protease of 25kDa, purified from the unripe fruits of Bromelia fastuosa, a wild South American Bromeliaceae. Proteolytic activity, measured using ...
Preliminary functional characterization, cloning and primary sequence of Fastuosain, a cysteine peptidase isolated from fruits of Bromelia fastuosa
(Bentham Science Publ Ltd, 2006-01-01)
The present work reports the characterization of Fastuosain, a novel cysteine protease of 25kDa, purified from the unripe fruits of Bromelia fastuosa, a wild South American Bromeliaceae. Proteolytic activity, measured using ...
Influência de inibidores proteicos e não-proteicos de proteases digestivas e caracterização bioquímico-cinética de cisteíno-proteases parcialmente purificadas de Anticarsia gemmatalisInfluence of proteinaceous and non-proteinaceous digestive protease inhibitors and kinetic biochemical characterization of cysteine-proteases partially purified of Anticarsia gemmatalis
(Universidade Federal de ViçosaBRBioquímica e Biologia molecular de plantas; Bioquímica e Biologia molecular animalDoutorado em Bioquímica AgrícolaUFV, 2015)
Theoretical insight into the mechanism for the inhibition of the cysteine protease cathepsin B by 1,2,4-thiadiazole derivatives
(Springer, 2014-06-01)
Several cellular disorders have been related to the overexpression of the cysteine protease cathepsin B (CatB), such as rheumatic arthritis, muscular dystrophy, osteoporosis, Alzheimer's disease, and tumor metastasis. ...
In silico-guided drug repurposing: identification of non-competitive inhibitors of Trypanosoma cruzi and Plasmodium falciparum cysteine proteases
(Fundación Revista Medicina, 2020)
Abstract/Resumen: Trypanosoma cruzi and Plasmodium falciparum are the etiologic agents of Chagas disease and Malaria, respectively. Cysteine proteases play key roles in the pathogenesis and survival of these parasites, ...
Inhibition of cysteine proteases by a natural biflavone: behavioral evaluation of fukugetin as papain and cruzain inhibitor
(Informa HealthcareLondon, 2013-08)
Cruzain is the major cysteine protease of Trypanosoma cruzi, the infectious agent responsible for Chagas disease, and cruzain inhibitors display considerable antitrypanosomal activity. In the present work we elucidated ...
The crystal structure of the cysteine protease Xylellain from Xylella fastidiosa reveals an intriguing activation mechanism
(Elsevier BVAmsterdam, 2013-02)
Xylella fastidiosa is responsible for a wide range of economically important plant diseases. We report here the crystal structure and kinetic data of Xylellain, the first cysteine protease characterized from the genome of ...