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Telomere shortening, ageing, and chromosome damage
(Elsevier B.V., 1996-07-31)
A relationship between telomere shortening and ageing has been established. A series of young and elderly healthy donors, Alzheimer disease patients, young and old Down's syndrome individuals were cytogenetically analyzed. ...
Chromosomal instability in chronic myeloid leukemia: Philadelphia breakpoints are independent of spontaneous breakage and fragile sites
(Ferrata Storti Foundation, 2000-10)
Increased frequencies of spontaneous and bromodeoxyuridine induced breakages with a non-random distribution of breakpoints were found in patients with chronic myeloid scientific correspondence 1105 Haematologica vol. ...
Cell death evaluation in benzo[a]pyrene-transformed human breast epithelial cells after microcell-mediated transfer of chromosomes 11 and 17
(Elsevier B.V., 2004-02-26)
The incidence of apoptosis and nuclear instability, including the incidence of catastrophic death, were investigated in benzo[a]pyrene (BP)-transformed human breast epithelial cells (BP1-E cell line) after microcell-mediated ...
Cell death evaluation in benzo[a]pyrene-transformed human breast epithelial cells after microcell-mediated transfer of chromosomes 11 and 17
(Elsevier B.V., 2004-02-26)
The incidence of apoptosis and nuclear instability, including the incidence of catastrophic death, were investigated in benzo[a]pyrene (BP)-transformed human breast epithelial cells (BP1-E cell line) after microcell-mediated ...
Structure, behaviour and repetitive DNA of B-chromosomes in Cestrum nocturnum (Solanaceae)
(Taylor & Francis Ltd, 2019-01)
The Cestrum genus is karyotypically exceptional in Solanaceae. It is characterised by a basic number x = 8, a large chromosomal and genomic size, complex heterochromatin patterns, B-chromosomes (Bs) with particular ...
Chromosomal Instability and Origin of B Chromosomes in the Amazonian Glass Tetra Moenkhausia oligolepis (Günther, 1864) (Characiformes, Characidae)
(2021-09-01)
B chromosomes occur in different species of the small characid fishes of the genus Moenkhausia. These supernumerary elements, that do not recombine with chromosomes of the standard A complement and follow their own ...
Streptonigrin induces delayed chromosomal instability involving interstitial telomeric sequences in Chinese hamster ovary cells
(Elsevier Science, 2012-08-30)
We analyzed the induction of chromosomal aberrations in Chinese hamster ovary (CHO) cells exposed to the radiomimetic compound streptonigrin (SN), in order to determine whether interstitial telomeric sequences (ITSs) are ...