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The protective role of vitamin D on the heart and the kidney
(SAGE Publications, 2017-01)
For a long time, vitamin D was regarded as an essential component for the maintenance of appropriate calcium metabolism. Indeed, the calcium-related functions were broadly studied and validated in numerous clinical and ...
Involvement of HDL receptor SR-BI-mediated vitamin E uptake in murine neural tube closure.
(2015)
SR-BI, the main HDL receptor, mediates the cellular uptake of cholesterol
and vitamin E. SR-BI is present in trophoblast giants cells (TGC) during
early pregnancy and 50% SR-BI-deficient (SR-BI / ) embryos die due to
defective ...
Vitamin D receptor levels and binding are reduced in aged rat intestinal subcelullar fractions
(Springer, 2008-12)
The hormonal form of vitamin D, 1α,25(OH)2-vitaminD3 [1α,25(OH)2D3], stimulates signal transduction pathways in intestinal cells. To gain insight into the relative importance of the vitamin D receptor (VDR) in the rapid ...
Vitamin D receptor gene FokI polymorphisms influence bone mass in adolescent football (soccer) players
(Springer Verlag (Germany), 2018)
Roles of the taql and bsml vitamin d receptor gene polymorphisms in hospital mortality of burn patients
(2016-08-01)
OBJECTIVE: The aim of this study was to evaluate the roles of the Taql and Bsml vitamin D receptor gene polymorphisms in hospital mortality of burn patients. METHODS: In total, 105 consecutive burn injury patients over 18 ...
Vitamin D receptor expression is associated with improved overall survival in human glioblastoma multiforme
(Springer, 2014-05)
Vitamin D and its analogs have been shown to display anti-proliferative effects in a wide variety of cancer types including glioblastoma multiforme (GBM). These anticancer effects are mediated by its active metabolite, 1α, ...
Heart Remodeling and Ischemia–Reperfusion Arrhythmias Linked to Myocardial Vitamin D Receptors Deficiency in Obstructive Nephropathy Are Reversed by Paricalcitol
(Sage Publications, 2014-06)
Cardiovascular disease is often associated with chronic kidney disease and vice versa; myocardial vitamin D receptors (VDRs) are among the probable links between the 2 disorders. The vitamin D receptor activator paricalcitol ...
Effect of nutritional vitamin A deficiency on lipid metabolism in the rat heart: Its relation to PPAR gene expression
(Elsevier Science Inc, 2009-07)
Objective: We studied the effect of dietary vitamin A deprivation on lipid composition and mRNA expression of regulatory enzymes involved in rat heart energetic lipid metabolism and its relation to the expression of ...
Daily oscillation of glutathione redox cycle is dampened in the nutritional vitamin A deficiency
(Taylor & Francis Ltd, 2012-08)
Examples of hormonal phase-shifting of circadian gene expression began to emerge a few years ago. Vitamin A fulfills a hormonal function by binding of retinoic acid to its nuclear receptors, RARs and RXRs. We found retinoid- ...
Age-related changes in the response of intestinal cells to 1α,25(OH)2-vitamin D3
(Elsevier Science, 2013-01)
The hormonally active form of vitamin D3, 1α,25(OH)2-vitamin D3, acts in intestine, its major target tissue, where its actions are of regulatory and developmental importance: regulation of intracellular calcium through ...