Buscar
Mostrando ítems 11-20 de 5626
Essential functional molecules associated with SARS-CoV-2 infection: Poten‐ tial therapeutic targets for COVID-19
The whole world is still suffering substantially from the coronavirus disease 2019 (COVID19) outbreak. Several protein-based molecules that are associated with the Severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2), ...
Bone Morphogenetic Proteins: Structure, biological function and therapeutic applications
(Elsevier B.V., 2014-11-01)
Bone Morphogenetic Proteins (BMPs) are multifunctional secreted cytokines, which belong to the TGF-beta superfamily. These glycoproteins act as a disulfide-linked homo- or heterodimers, being potent regulators of bone and ...
ERp57 as a novel cellular factor controlling prion protein biosynthesis: Therapeutic potential of protein disulfide isomerases
(TAYLOR & FRANCIS, 2016)
Disturbance of endoplasmic reticulum (ER) proteostasis is observed in Prion-related disorders (PrDs). The protein disulfide isomerase ERp57 is a stress-responsive ER chaperone up-regulated in the brain of Creutzfeldt-Jakob ...
Lactoferrin for prevention of neonatal sepsis
(Springer, 2014)
Preterm neonates are at risk to acquire infections. In addition to the high mortality associated with sepsis, these patients are at risk for long-term disabilities, particularly neurodevelopment impairment. Several ...
Bone Morphogenetic Proteins: Structure, biological function and therapeutic applications
(Elsevier B.V., 2015)
Advancements in the co-formulation of biologic therapeutics
Biologic therapeutics are the medicines of the future and are destined to transform the approaches
by which the causes and symptoms of diseases are cured and alleviated. These approaches will
be accelerated through the ...
Targeting SARS-CoV2 spike protein receptor binding domain by therapeutic antibodies
As the number of people infected with the newly identified 2019 novel coronavirus (SARSCoV2) is continuously increasing every day, development of potential therapeutic platforms is
vital. Based on the comparatively high ...
Musashi-1 RNA binding protein a new biomarker candidate and therapeutic target in urothelial carcinoma.
(Wiley-Blackwell, 2018-09-01)