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The oestrogen metabolite 2-methoxyoestradiol alone or in combination with tumour necrosis factor-related apoptosis-inducing ligand mediates apoptosis in cancerous but not healthy cells of the human endometrium
(BIOSCIENTIFICA LTD, 2007)
Cancers of the reproductive tract account for 12% of all malignancies in women. As previous studies have shown that oestrogen metabolites can cause apoptosis, we characterised the effect of oestrogen and oestrogen metabolites ...
Neuroactive Steroids in Hypoxic–Ischemic Brain Injury: Overview and Future Directions
(IntechOpen, 2020)
Hypoxic?ischemic brain injury is a number one cause of long-term neurologic dis- ability and death worldwide. This public health burden is mainly characterized by a decrease in oxygen concentration and blood flow to the ...
Receptores estrogênicos regulam a migração e a invasão das células de câncer prostático independentes de andrógenos Pc-3
(Universidade Federal de São Paulo (UNIFESP), 2018-11-28)
Recent studies from our laboratory have shown the expression of estrogen
receptors ESR1 (ERα) and ESR2 (ERβ) in androgenindependent
prostate cancer cells
(PC3),
used as castrationresistant
prostate cancer models. ...
A review of analytical methods for the determination of tibolone: Phar-macokinetics and pharmaceutical formulations analysis and application in doping control
(2021-01-01)
Background: Tibolone is a synthetic steroid commercialized by Organon under the brand name Livial (Org OD14), which is used in hormone therapy for menopause management and treatment of postmenopausal osteoporosis. Tibolone ...
New molecular approches using AR, FOXA1 and HER2 for outcome classification of estrogen Receptor-Positive (ER+) breast cancers”
(Universidad del RosarioDoctorado en Ciencias BiomédicasFacultad de Ciencias Naturales y Matemáticas, 2018)
Here, we studied new prognostic and predictive easy access strategies in breast cancer (molecular markers), for better classify ER+ breast cancer disease, which might provide additional information and be complementary to ...