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Development of Novel Efficient SIN Vectors with Improved Safety Features for Wiskott–Aldrich Syndrome Stem Cell Based Gene Therapy
(American Chemical Society, 2011-10)
Gene therapy is a promising therapeutic approach to treat primary immunodeficiencies. Indeed, the clinical trial for the Wiskott–Aldrich Syndrome (WAS) that is currently ongoing at the Hannover Medical School (Germany) has ...
Characterizatión and use of retroviral internal ribosome entry segments (ires) for the development or bicistronic retroviral vectors for an efficient gene transfer
(1999)
Los vectores retrovirales se han perfilado como uno de las herramientas más importantesen la transferencia de genes. De hecho, han permitido la transducción de genes conpotencialidad terapéutica a múltiples tipos celulares ...
Characterizatión and use of retroviral internal ribosome entry segments (ires) for the development or bicistronic retroviral vectors for an efficient gene transfer
(1999)
Los vectores retrovirales se han perfilado como uno de las herramientas más importantesen la transferencia de genes. De hecho, han permitido la transducción de genes conpotencialidad terapéutica a múltiples tipos celulares ...
Stable and high-level production of recombinant Factor IX in human hepatic cell line
(WILEY-BLACKWELL, 2011)
Hemophilia B is a genetic disease of the coagulation system that affects one in 30,000 males worldwide. Recombinant human Factor IX (rhFIX) has been used for hemophilia B treatment, but the amount of active protein generated ...
High-level expression of mouse growth hormone (mGH) by primary human keratinocytes using a retroviral vector
(Sao Paulo: SBBq, 2002, 2014)
Anti-tumor effect of endostatin mediated by retroviral gene transfer in mice bearing renal cell carcinoma
(Federation Amer Soc Exp Biol, 2007-10-01)
We investigated whether transfer of the gene encoding the angiogenesis inhibitor endostatin into the NIH/3T3 fibroblast cell line could inhibit renal tumor growth in vivo. NIH/3T3 cells were transduced with retroviral ...