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Placental steroidogenesis in pregnant women with polycystic ovary syndrome
(Elsevier, 2013)
Objective: To evaluate the placental activity of steroid sulfatase (STS), 3b-hydroxysteroid dehydrogenase
type 1 (3b-HSD-1) and P450 aromatase (P450arom) in polycystic ovarian syndrome (PCOS) compared to
normal pregnant ...
Human Aromatase Deficiency
(Biomedical Research Press Ltd, 2018-01)
Several molecular CYP19A1 gene alterations associated with cytochrome P450 aromatase (cP450arom) deficiency have been describedin both females and males. This has contributed considerably to the understanding of cP450arom ...
Pregnancy and lactation differentially modify the transcriptional regulation of steroidogenic enzymes through DNA methylation mechanisms in the hippocampus of aged rats
(Elsevier Ireland, 2016-07)
In the present study, we examined the mRNA expression and DNA methylation state of steroidogenic enzymes in the hippocampus of young adult (90-days-old) and middle-aged (450-days-old) nulliparous rats, and middle-aged ...
Immunolocalization of steroidogenic enzymes in the vaginal mucous of Galea spixii during the estrous cycle
(BioMed Central, 2017)
Abstract
Background
The synthesis of sex steroids is controlled by several enzymes such as17α-hydroxylase cytochrome P450 (P450c17) catalyzing androgen synthesis and aromatase ...
Disruption in the expression and immunolocalisation of steroid receptors and steroidogenic enzymes in letrozole-induced polycystic ovaries in rat
(Csiro Publishing, 2009-12)
The objective of the present study was to characterise the expression and tissue distribution of steroid receptors (oestrogen receptor- and (ER, ER), androgen receptor (AR) and progesterone receptor (PR)) and steroidogenic ...
Immunolocalization of steroidogenic enzymes in the vaginal mucous of Galea spixii during the estrous cycle
(2017-04-24)
Abstract
Background
The synthesis of sex steroids is controlled by several enzymes such as17α-hydroxylase cytochrome P450 (P450c17) catalyzing androgen synthesis and aromatase ...
Alterations in folliculogenesis in women with polycystic ovary syndrome
(Pergamon-Elsevier Science Ltd, 2011-03)
The objective of the present study was to examine some factors involved in follicular development of women with polycystic ovary syndrome (PCOS). Women with PCOS showed increased levels of serum luteinizing hormone (LH) ...
Oestrogens and Progestagens: Synthesis and Action in the Brain
(Wiley Blackwell Publishing, Inc, 2016-07)
When steroids, such as pregnenolone, progesterone and oestrogen, are synthesised de novo in neural tissues, they are more specifically referred to as neurosteroids. These neurosteroids bind specific receptors to promote ...