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Pathogenic effects of maternal antinuclear antibodies during pregnancy in women with lupus
(PAGEPress, 2014)
Lupus is an autoimmune disease that primarily affects young women of childbearing
age. Fertility rates in lupus patients depend on various factors, including disease activity,
nephritis, and the presence of antiphospholipid ...
Localization of Cathepsins D and B at the Maternal-Fetal Interface and the Invasiveness of the Trophoblast during the Postimplantation Period in the Mouse
(KARGER, 2011)
A survey of existing data suggests that trophoblast cells produce factors involved in extracellular matrix degradation. In this study, we correlated the expression of cathepsins D and B in the murine ectoplacental cone ...
Vasoactive intestinal peptide induces an immunosuppressant microenvironment in the maternal fetal interface of non-obese diabetic mice and improves early pregnancy outcome
(Wiley, 2014-02)
PROBLEM: Impaired pregnancy in non-obese diabetic (NOD) mice was related to limited vascular remodeling and autoimmune background. Vasoactive intestinal peptide (VIP) has anti-inflammatory and immunosuppressant effects, ...
NK cell-derived IL-10 is critical for DC-NK cell dialogue at the maternal-fetal interface
(Nature Publishing Group, 2017-12)
DC-NK cell interactions are thought to influence the development of maternal tolerance and de novo angiogenesis during early gestation. However, it is unclear which mechanism ensures the cooperative dialogue between DC and ...
Immunization with inactivated antigens of Neospora caninum induces tolllike receptors 3, 7, 8 and 9 in maternal-fetal interface of infected pregnant heifers
(2017)
Neospora caninum is an obligate parasite and a major cause of abortion in cattle. Pregnancy failures appear to be associated with weak innate defences on the maternal-fetal interface during infection with N. caninum. Herein, ...
Trypanosoma cruzi infection at the maternal-fetal interface: Implications of parasite load in the congenital transmission and challenges in the diagnosis of infected newborns
(Frontiers Media S.A., 2019-06-07)
Trypanosoma cruzi is the protozoan unicellular parasite that causes Chagas disease. It can be transmitted from infected mothers to their babies via the connatal route, thus being able to perpetuate even in the absence of ...
Profiling Lgals9 splice variant expression at the fetal-maternal interface: implications in normal and pathological human pregnancy
(Oxford University Press, 2013)
Disruption of fetal-maternal tolerance mechanisms can contribute to pregnancy complications, including spontaneous abortion. Galectin-9 (LGALS9), a tandem repeat lectin associated with immune modulation, is expressed in ...
Placentation in cloned cattle: Structure and microvascular architecture
(Elsevier B.V., 2007-09-01)
To elucidate the morphological differences between placentas from normal and cloned cattle pregnancies reaching term, the umbilical cord, placentomes and interplacentomal region of the fetal membranes were examined ...
Placentation in cloned cattle: Structure and microvascular architecture
(Elsevier B.V., 2007-09-01)
To elucidate the morphological differences between placentas from normal and cloned cattle pregnancies reaching term, the umbilical cord, placentomes and interplacentomal region of the fetal membranes were examined ...
IFPA meeting 2016 workshop report III: Decidua trophoblast interactions; trophoblast implantation and invasion; immunology at the maternal fetal interface; placental inflammation
(Elsevier, 2017)
Workshops are an important part of the IFPA annual meeting as they allow for discussion of specialised topics. At IFPA meeting 2016 there were twelve themed workshops, four of which are summarized in this report. These ...