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MicroRNAs expression influence in ulcerative colitis and Crohn's disease: A pilot study for the identification of diagnostic biomarkers
(2021-12-07)
from the Pathology Department of Botucatu Medical School at São Paulo State University (Unesp). The diagnosis of UC or CD was based on clinical, endoscopic, radiologic, and histological criteria and confirmed by histopathological ...
Use of Mature miRNA Strand Selection in miRNAs Families in Cervical Cancer Development
(MDPI, 2017-02-14)
Aberrant miRNA expression is well recognized as a cancer hallmark, nevertheless miRNA functionandexpressiondoesnotalwayscorrelateinpatientstissuesandcelllinesstudies. Inaddition to this issue, miRNA strand usage conduces ...
Análise de microRNAs (miRNAs) em Líquen Plano Bucal
(Universidade Federal de Minas GeraisUFMG, 2011-07-20)
Oral lichen planus (OLP) is a chronic inflammatory disease that is Th1-mediated and affects the oral mucosa with a variety of clinical presentations. Interferon-gamma (IFN-) is an important cytokine involved in the regulation ...
Involvement of miRNAs and cell-secreted vesicles in mammalian ovarian antral follicle development
(2015)
Ovarian follicular development is a controlled series of events culminating with an ovulatory or atretic follicle. MicroRNAs (miRNAs) are small noncoding RNAs involved in translational regulation of genes in different ...
Identificação de SNPs em sequências de microRNAs de suínos e os possíveis efeitos na predição de transcritos alvo
(Universidade Estadual Paulista (Unesp), 2019-05-27)
Os microRNAs (miRNAs) são pequenos RNAs não-codificadores (20-22 nucleotídeos) que exercem uma função de controle pós-transcricional em RNA mensageiro (RNAm), regulando a produção de proteínas. Variações genéticas, como ...
Caracterización de miRNAs involucrados en respuesta a infección por bacterias del género Xanthomonas en arroz y yuca
(2012)
Los microRNAs (miRNAs) son moléculas de RNAs pequeñas que juegan un papel importante en la regulación de la expresión génica en eucariotas mediante el silenciamiento de mRNAs complementarios (targets). En este trabajo se ...
Microribonucleic acid-21 increases aldosterone secretion and proliferation in H295R human adrenocortical cells
(ENDOCRINE SOC, 2008)
MicroRNAs (miRNAs) are endogenous small noncoding RNAs that decrease the expression levels of specific genes by translational repression, sequestration, and degradation of their mRNAs. Angiotensin II is an important modulator ...
Potent degradation of neuronal miRNAs induced by highly complementary targets
(Nature Publishing Group, 2015-04)
MicroRNAs (miRNAs) regulate target mRNAs by silencing them. Reciprocally, however, target mRNAs can also modulate miRNA stability. Here, we uncover a remarkable efficacy of target RNA-directed miRNA degradation (TDMD) in ...
MicroRNA-33b is a potential non-invasive biomarker for response to atorvastatin treatment in chilean subjects with hypercholesterolemia: a pilot study
(Frontiers Media, 2021)
Evidence accumulated so far indicates that circulating levels of microRNAs (miRNAs) are associated with several pathologies. Therefore, differential expression of extracellular miRNAs exhibits promising potential for ...
HASTY modulates miRNA biogenesis by linking pri-miRNA transcription and processing
(Oxford University Press, 2021-03)
HASTY, the plant ortholog of human exportin 5, was proposed to export miRNAs from the nucleus to the cytoplasm, whereas this has long been disputed. This study shows that HASTY, rather than acting as a miRNA cargo protein, ...