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Mostrando ítems 11-20 de 1799
Vias de sinalização de proteínas MAPKS em Schistosoma mansoni
(Universidade Federal de Minas GeraisBrasilPrograma de Pós-Graduação em BioinformaticaUFMG, 2017-04-27)
MAPK pathways regulation by DUSP1 in the development of osteosarcoma: Potential markers and therapeutic targets
(Wiley, 2017)
Osteosarcoma (OS) is the most frequent primary bone tumor that affect children and adolescents. This tumor is highly aggressive with high risk of metastasis and the implementation of new drugs has not been successful. The ...
Envolvimento de p38 MAPK no ciclo de vida do Vaccinia virus
(Universidade Federal de Minas GeraisBrasilICB - DEPARTAMENTO DE MICROBIOLOGIAPrograma de Pós-Graduação em MicrobiologiaUFMG, 2014-02-27)
Viruses rely extensively on host cell functions to complete their lifecycles. During infection, viruses co-opt signaling pathways, key regulators of cell physiology, to achieve an intracellular milieu suitable for productive ...
The role of p38 mitogen-activated protein kinase in serum-induced leukemia inhibitory factor secretion by bone marrow stromal cells from pediatric myelodysplastic syndromes
(PERGAMON-ELSEVIER SCIENCE LTD, 2010)
Stromal cells from pediatric myelodysplastic syndromes (MDS) and acute myeloid leukemia (AML) associated with MDS(MDS-AML) present high expression of leukemia inhibitor factor (LIF). We demonstrated using mitogen-activated ...
Estudo do perfil de ativação da via MAPK em células Hela induzido por formas Amastigotas Extracelulares (AEs) das cepas G e CL de Trypanosoma cruzi
(Universidade Federal de Minas GeraisBrasilICB - DEPARTAMENTO DE BIOLOGIA GERALPrograma de Pós-Graduação em GenéticaUFMG, 2019-02-28)
Trypanosoma cruzi, the etiologic agent of Chagas Disease, which affects about 7 millions people induces MAPK pathway activation during cell invasion, favoring its entry and survival. Mitogen-activated protein kinases (MAPKs) ...
Tert Promoter Mutations In Melanoma Render Tert Expression Dependent On Mapk Pathway Activation
(Impact Journals LlcAlbany, 2016)
The Potential of p38 MAPK Inhibitors to Modulate Periodontal Infections
(Bentham Science Publ Ltd, 2009-01-01)
Periodontal disease initiation and progression occurs as a consequence of the host immune inflammatory response to oral pathogens. The innate and acquired immune systems are critical for the proper immune response. LPS, ...
The Potential of p38 MAPK Inhibitors to Modulate Periodontal Infections
(Bentham Science Publ Ltd, 2009-01-01)
Periodontal disease initiation and progression occurs as a consequence of the host immune inflammatory response to oral pathogens. The innate and acquired immune systems are critical for the proper immune response. LPS, ...
The Potential of p38 MAPK Inhibitors to Modulate Periodontal Infections
(Bentham Science Publ Ltd, 2013)
Docking, synthesis and pharmacological activity of novel urea-derivatives designed as p38 MAPK inhibitors
(ELSEVIER FRANCE-EDITIONS SCIENTIFIQUES MEDICALES ELSEVIERPARIS, 2012)
p38 mitogen-activated protein kinase (p38 MAPK) is an important signal transducing enzyme involved in many cellular regulations, including signaling pathways, pain and inflammation. Several p38 MAPK inhibitors have been ...