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Intracellular and extracellular pH dynamics in the human placenta from diabetes mellitus
(2016-07-01)
The placenta is a vital organ whose function in diseases of pregnancy is altered, resulting in an abnormal supply of nutrients to the foetus. The lack of placental vasculature homeostasis regulation causes endothelial ...
Abortive and propagating intracellular calcium waves: Analysis from a hybrid model
(Public Library of Science, 2015-01)
The functional properties of inositol(1,4,5)-triphosphate (IP3) receptors allow a variety of intracellular Ca2+ phenomena. In this way, global phenomena, such as propagating and abortive Ca2+ waves, as well as local events ...
Connexin hemichannels and pannexin channels contributes to the intracellular Ca2+ signal activated by PAF in endothelial cells of mesenteric post-capillary venules
(2016)
Endothelial cells form a permeability barrier to macromolecules that can be modulated in post-capillary venules through the activation of Ca2+-dependent signaling pathways by pro-inflammatory agents, such as platelet-activating ...
Interaction between the lateral preoptic area and the subfornical organ in the control of water ingestion caused by cellular dehydration, hypotension, hypovolemia, and deprivation
(1980-01-01)
Water intake was studied in albino rats with lesions in the lateral preoptic area, in the subfornical organ, and in both the lateral preoptic area and the subfornical organ. Drinking was induced by cellular dehydration, ...
Interaction between the lateral preoptic area and the subfornical organ in the control of water ingestion caused by cellular dehydration, hypotension, hypovolemia, and deprivation
(1980-01-01)
Water intake was studied in albino rats with lesions in the lateral preoptic area, in the subfornical organ, and in both the lateral preoptic area and the subfornical organ. Drinking was induced by cellular dehydration, ...
Spatial-Memory Formation After Spaced Learning Involves ERKs1/2 Activation Through a Behavioral-Tagging Process
(Nature, 2020-12)
The superiority of spaced over massed learning is an established fact in the formation of long-term memories (LTM). Here we addressed the cellular processes and the temporal demands of this phenomenon using a weak spatial ...
Estradiol-mediated axogenesis of hypothalamic neurons requires ERK1/2 and ryanodine receptors-dependent intracellular Ca2+ rise in male rats
(Frontiers Media S.A., 2019-01)
17β-estradiol (E2) induces axonal growth through extracellular signal-regulated kinase 1 and 2 (ERK1/2)-MAPK cascade in hypothalamic neurons of male rat embryos in vitro, but the mechanism that initiates these events is ...