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Nuclear action of FGF members in endocrine-related tissues and cancer: interplay with steroid receptor pathways
(Elsevier Science Inc, 2019-09)
Dysregulation of the fibroblast growth factors/fibroblast growth factor receptor (FGF/FGFR) pathway has been implicated in a wide range of human disorders and several members have been localized in the nuclear compartment. ...
Effect of cholecystectomy on bile acid synthesis and circulating levels of fibroblast growth factor 19
(2015)
Background and rationale for the study. FGF19/15 is a gut-derived hormone presumably governing bile acid (BA) synthesis and gallbladder (GB) refilling. FGF19 mRNA is present in human GB cholangiocytes (hGBECs); however, ...
Deficiency of fibroblast growth factor 2 (FGF-2) leads to abnormal spermatogenesis and altered sperm physiology
(Wiley-liss, Div John Wiley & Sons Inc, 2018-12)
In previous studies, we described the presence of fibroblast growth factor 2 (FGF-2) and its receptors (FGFRs) in human testis and sperm, which are involved in spermatogenesis and in motility regulation. The aim of the ...
Expressão e função de membrso das subfamílias FGF-8 e FGF-9 em folículos antrais bovinos
(Universidade Estadual Paulista (UNESP), 2014)
Rol de Klotho y FGF23 en la regulación de fosfato y calcio plasmático
(Hospital Clínico Universidad de Chile, 2010)
Recently, two proteins have been discovered, named Klotho and FGF23, which are involved in several physiologic phenomena. One of the most relevant is the reduction of phosphatemia and the increase of phosphaturia. This ...
Expression of fibroblast growth factors 17 and 18 (Fgf-17 and Fgf-18) in bovine antral follicles
(Soc Study Reproduction, 2008-01-01)
Expression of fibroblast growth factors 17 and 18 (Fgf-17 and Fgf-18) in bovine antral follicles
(Soc Study Reproduction, 2008-01-01)
Erythropoietin induces bone marrow and plasma fibroblast growth factor 23 during acute kidney injury
(Elsevier, 2018)
It is accepted that osteoblasts/osteocytes are the major source for circulating fibroblast growth factor 23 (FGF23). However, erythropoietic cells of bone marrow also express FGF23. The modulation of FGF23 expression in ...
Fibroblast growth factor 2 regulates cumulus differentiation under the control of the oocyte
(Springer, 2019-05-01)
PurposeWe first assessed regulation of FGF2 expression in cumulus cells by FSH and oocyte-secreted factors during in vitro maturation (IVM). Then, we tested the hypothesis that FGF2 regulates meiotic progression, cumulus ...
Increased high molecular weight FGF2 in endocrine-resistant breast cancer
(Springer US, 2018-10)
Endocrine resistance may develop as a consequence of enhanced growth factor signaling. Fibroblast growth factor 2 (FGF2) consists of a low and several high molecular weight forms (HMW-FGF2). We previously demonstrated that ...