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Leucemia Promielocítica Aguda na infância: estudo cromossômico e investigação da ocorrência de mutações nos genes FLT3 e NPM1 e sua importância prognóstica
(Universidade Federal de Pernambuco, 2015)
Análise de mutações nos genes NPM1 e IDH1 e sua associação com características clínicas e biológicas em pacientes com leucemia mielóide aguda
(Universidade Federal de Minas GeraisUFMG, 2014-07-09)
In adults patients with AML and normal karyotype, risk stratification is a challenge. In this group, mutations in the genes NPM1 and IDH1 have been analyzed for their prognostic value. This work aimed to evaluate the ...
Identificação de alterações genéticas ao diagnóstico e correlação com características clínicas e laboratoriais e evolução em pacientes com leucemia mielóide aguda
(Universidade Federal de Minas GeraisUFMG, 2014-07-01)
The prevalence, the prognostic effect, and interaction with other molecular markers of DNMT3A mutations were studied in 415 adults patients with acute myeloid leukemia (AML) younger than 60 years, regarding its prognostic ...
High expression of AURKA and AURKB is associated with unfavorable cytogenetic abnormalities and high white blood cell count in patients with acute myeloid leukemia
(PERGAMON-ELSEVIER SCIENCE LTD, 2011)
In the present study, we analyzed AURKA and AURKB gene expression in 70 acute myeloid leukemia (AML) patients. There was no difference between leukemic samples and bone marrow mononuclear cells (BMMCs, n = 8) or CD34(+) ...
Arranjos De Polimorfismos De Nucleotídeo Único (Snp Array) E Sequenciamento De Nova Geração (Ngs) Na Avaliação E Detecção De Anormalidades Genético-Moleculares Na Leucemia Mieloide Aguda (Lma
(Universidade Federal de São Paulo (UNIFESP), 2017-10-04)
Introduction: Acute myeloid leukemia (AML) is the most frequent leukemia in adults and results from somatic genetic lesions on hematopoietic progenitor cells that modify the normal life cycle of cells. The karyotype ...
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