Buscar
Mostrando ítems 11-20 de 276
Effects of a selective cyclooxygenase-2 inhibitor on endometrial epithelial cells from patients with endometriosis
(Oxford University Press, 2008)
Celecoxib, a selective cyclooxygenase (COX)-2 inhibitor, also has anti-proliferative properties and pro-apoptotic effects on different in vivo and in vitro models, two actions that may be efficacious in therapy for ...
Lack of effect of naltrexone on the spinal synergism between morphine and non steroidal anti-inflammatory drugs
(Polish Academy of Sciences, 2009)
To enhance analgesia, the combinatorial use of analgesic drugs with proven efficacies is a widely-used strategy to reduce adverse side effects. The present study characterizes the antinociceptive interaction of intrathecal ...
Análise in silico, in vitro e in vivo de compostos organocalcogênios como possíveis anti-inflamatórios
(Universidade Federal de São CarlosUFSCarPrograma de Pós-Graduação em Biotecnologia - PPGBiotecCâmpus São Carlos, 2015-06-30)
In this work are presented the in silico study of the formation of complexes between organochalcogens compounds with enzymes COX-1 and COX-2 that were carried out in order to study their potential to act as selective ...
Cellular and molecular studies of the effects of a selective COX-2 inhibitor celecoxib in the cardiac cell line H9c2 and their correlation with death mechanisms
(Associação Brasileira de Divulgação Científica (ABRADIC), 2014-01-01)
Cardiovascular disease is one of the leading causes of death worldwide, and evidence indicates a correlation between the inflammatory process and cardiac dysfunction. Selective inhibitors of cyclooxygenase-2 (COX-2) enzyme ...
Effect of COX-2 inhibitor after TNBS-induced colitis in wistar rats
(Springer, 2009-08-01)
Inflammatory bowel disease (IBD) is a common chronic gastrointestinal disorder characterized by alternating periods of remission and active intestinal inflammation. Some studies suggest that antiinflammatory drugs are a ...
Lack of effect of naltrindole on the spinal synergism of morphine and non-steroidal anti-inflammatory drugs (NSAIDS)
(2009)
To enhance analgesia, combination of analgesics drugs of proven efficacy is a strategy which is accompanied by a reduction of adverse effects. The present study was undertaken to characterize the antinociceptive interaction ...
Role of selective cyclo-oxygenase-2 inhibitor celecoxib in canine osteosarcoma cell culture
(2013)
Background: Experimental studies have shown that cyclo-oxygenase-2 (Cox2) is related to the development and progression of tumors, since this enzyme is induced and expressed by cells such as macrophages, osteoblasts, ...
Selective Cox-2 Inhibitor (meloxicam) And Tooth-supporting Bone Quality. A Histomorphometric Study In Rats
(Fundação Odontológica de Ribeirão Preto, 2017)
Prostaglandin involvement in hyperthermia induced by sleep deprivation: A pharmacological and autoradiographic study
(Elsevier B.V., 2009-02-27)
Aims: Hyperthermia is a characteristic functional effect of sleep deprivation (SD). We hypothesize here that prostaglandin E2 (PGE2) could be involved in hyperthermia induced by sleep deprivation.Main methods: To address ...