info:eu-repo/semantics/article
Effects of a selective cyclooxygenase-2 inhibitor on endometrial epithelial cells from patients with endometriosis
Fecha
2008Registro en:
Olivares, Carla Noemi; Bilotas, Mariela Andrea; Buque, Ricardo; Borghi, Mario; Sueldo, Carlos; et al.; Effects of a selective cyclooxygenase-2 inhibitor on endometrial epithelial cells from patients with endometriosis; Oxford University Press; Human Reproduction; 23; 12; 2008; 2701-2708
0268-1161
1460-2350
CONICET Digital
CONICET
Autor
Olivares, Carla Noemi
Bilotas, Mariela Andrea
Buque, Ricardo
Borghi, Mario
Sueldo, Carlos
Tesone, Marta
Meresman, Gabriela Fabiana
Resumen
Celecoxib, a selective cyclooxygenase (COX)-2 inhibitor, also has anti-proliferative properties and pro-apoptotic effects on different in vivo and in vitro models, two actions that may be efficacious in therapy for endometriosis. We evaluated the effects of celecoxib on apoptosis and proliferation, and vascular endothelial growth factor (VEGF) production and COX-2 expression and activity in endometrial epithelial cells (EECs).