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Histamine H4 receptor : insights into a potential therapeutic target in breast cancer
(2015)
Abstract: Breast cancer is the second most common cancer worldwide, and the leading cause of cancer
death in women. Several studies underlined the critical role of histamine in breast cancer development and
progression. ...
IDO is highly expressed in breast cancer and breast cancer-derived circulating microvesicles and associated to aggressive types of tumors by in silico analysis
(Karger, 2014-07)
Indoleamine-2,3-dioxygenase (IDO) has been established as a normal mechanism of peripheral tolerance and immunosuppression. Besides, malignant tumors release microvesicles (MV) related with tumor dissemination. The aims ...
C-kit (CD117) is a uniform marker of non-neoplastic breast tissue and is also expressed in a unique subset of breast cancers
(Lippincott Williams & Wilkins, 1999-01-01)
Human breast adipose tissue: characterization of factors that change during tumor progression in human breast cancer
(BioMed Central, 2017-02-07)
Adipose microenvironment is involved in signaling pathways that influence breast cancer. We aim to characterize factors that are modified: 1) in tumor and non tumor human breast epithelial cell lines when incubated with ...
Down-regulation of the candidate tumor suppressor gene PAR-4 is associated with poor prognosis in breast cancer
(SPANDIDOS PUBL LTD, 2010)
Substantial experimental evidence indicates that PAWR gene (PKC apoptosis WT1 regulator; also named PAR-4, prostate apoptosis response-4) is a central player in cancer cell survival and a potential target for cancer-selective ...
Molecular aspects of breast cancer resistance to drugs (Review)
(Spandidos Publ, 2015)
Despite continuous advances in the knowledge of breast cancer pathophysiology, this type of
neoplasia remains a leading cause of cancer-related death in women worldwide.
Carcinogenesis takes a progressive course from ...
Can Breast Tumors Affect the Oxidative Status of the Surrounding Environment? A Comparative Analysis among Cancerous Breast, Mammary Adjacent Tissue, and Plasma
(Hindawi Ltd, 2016-01-01)
In this paper, we investigated the oxidative profile of breast tumors in comparison with their normal adjacent breast tissue. Our study indicates that breast tumors present enhanced oxidative/nitrosative stress, with ...
Nonproliferative epithelial alteration and expression of estrogen receptor and Ki67 in the contralateral breast of women treated with tamoxifen for breast cancer
(Churchill LivingstoneEdinburghEscócia, 2007)