Artículos de revistas
Can Breast Tumors Affect the Oxidative Status of the Surrounding Environment? A Comparative Analysis among Cancerous Breast, Mammary Adjacent Tissue, and Plasma
Fecha
2016-01-01Registro en:
Oxidative Medicine And Cellular Longevity. London: Hindawi Ltd, 9 p., 2016.
1942-0900
10.1155/2016/6429812
WOS:000372235600001
WOS000372235600001.pdf
Autor
State Univ West Parana UNIOESTE
Universidade Estadual Paulista (Unesp)
Pontificia Univ Catolica
Universidade Estadual de Londrina (UEL)
Universidade de São Paulo (USP)
Institución
Resumen
In this paper, we investigated the oxidative profile of breast tumors in comparison with their normal adjacent breast tissue. Our study indicates that breast tumors present enhanced oxidative/nitrosative stress, with concomitant augmented antioxidant capacity when compared to the adjacent normal breast. These data indicate that breast cancers may be responsible for the induction of a prooxidant environment in the mammary gland, in association with enhanced TNF-alpha and nitric oxide.