Buscar
Mostrando ítems 11-20 de 581
Prevalence of BRCA1 and BRCA2 Mutations in Unselected Breast Cancer Patients from Medellín, Colombia
(BMC (BioMed Central)Genética MédicaPoznań, Polonia, 2023)
Analysis of 5382insC (BRCA1) and 6174delT (BRCA2) mutations in 382 healthy Chilean women with a family history of breast cancer
(Sociedad de Biología de Chile, 2002)
Transcriptional Autoregulation by BRCA1
(American Association For Cancer Research, 2010-01)
The BRCA1 gene product plays numerous roles in regulating genome integrity. Its role in assembling supermolecular complexes in response to DNA damage has been extensively studied; however, much less is understood about its ...
Determinación de una mutación en el gen BRCA1 en una familia que presenta cáncer de mama hereditario
(Sociedad Médica de Santiago, 2004)
Germline mutations in BRCA1 and BRCA2 in epithelial ovarian cancer patients in Brazil
(BioMed Central, 2016)
Abstract
Background
Approximately 8–15% epithelial ovarian cancer patients are BRCA1 or BRCA2 germline mutation carriers. Brazilian inhabitants may have peculiar genetic ...
Frequency of sequence mutations and variants for the BRCA1 and BRCA2 genes in a sample of Colombian women with suspected hereditary breast cancer syndrome: Case seriesFrecuencia de mutación y de variantes de secuencia para los genes BRCA1 y BRCA2 en una muestra de mujeres colombianas con sospecha de síndrome de cáncer de mama hereditario: serie de casos
(Rev. Colomb. Obstet. Ginecol., 2015-12-21)
Objective: To describe sequence variants in the BRCA1 and BRCA2 genes in a sample of Colombian patients with a personal or family histor y of breast cancer suggestive of genetic risk. Materials and methods: Case ...
Promoter hypermethylation of BRCA1 correlates with absence of expression in hereditary breast cancer tumors
(TAYLOR & FRANCIS INC, 2008)
Germline mutations in BRCA1 account for a low proportion of hereditary cases in diverse populations. Several efforts have been made to find new genes involved in the inheritance of breast cancer with no success until today. ...
Promoter hypermethylation of BRCA1 correlates with absence of expression in hereditary breast cancer tumors
Germline mutations in BRCA1 account for a low proportion of hereditary cases in diverse populations. Several efforts have been made to find new genes involved in the inheritance of breast cancer with no success until today. ...
Mutations in BRCA1, BRCA2 and other breast and ovarian cancer susceptibility genes in Central and South American populations
(2017)
Breast cancer (BC) is the most common malignancy among women worldwide. A major advance in the understanding of the genetic etiology of BC was the discovery of BRCA1 and BRCA2 (BRCA1/2) genes, which are considered ...