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Promotion of Neutrophil Apoptosis by TNF- α
(American Association of Immunologists, 2001-03)
We examined the ability of TNF-α to modulate human neutrophil apoptosis. Neutrophils cultured with TNF-α alone undergo a low but significant increase in the number of apoptotic cells. More interestingly, when neutrophils ...
Interactions with apoptotic but not with necrotic neutrophils increase parasite burden in human macrophages infected with Leishmania amazonensis
(2008)
Neutrophils are involved in the initial steps of most responses to pathogens. In the present study, we evaluated the effects of the interaction of apoptotic vs. necrotic human neutrophils on macrophage infection by Leishmania ...
Neutrophil apoptosis in the context of tuberculosis infection
(Churchill Livingstone, 2015-07)
Polymorphonuclear neutrophils comprise two-thirds of peripheral blood leukocytes and are key components of innate immunity as a first line of defense against bacterial and fungal pathogens. Their microbicidal mechanisms ...
Regulation of neutrophil apoptosis by cytokines, pathogens and environmental stressors
(Frontiers in Bioscience, 2009-01)
As a key component of the innate immune response, neutrophils play a major role in host protection against bacterial and fungi infections. Neutrophils are short-lived phagocytic cells and, as a first line of defense against ...
Trophoblast cells inhibit neutrophil extracellular trap formation and enhance apoptosis through vasoactive intestinal peptide-mediated pathways
(Oxford University Press, 2016-12)
STUDY QUESTION:Do human trophoblast cells modulate neutrophil extracellular trap (NET) formation, reactive oxygen species (ROS) synthesis and neutrophil apoptosis through mechanisms involving vasoactive intestinal peptide ...
Efeito do plasma rico em glicose na apoptose de neutrófilos de cães
(2013-12-01)
Hyperglycemia is considered the main cause of increased mortality in diabetic humans, to promote the acceleration of neutrophil apoptosis, essential for the functioning of the immune system. Thus, there is an immunosuppressive ...