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Vascular activity of (-)-anonaine, (-)-roemerine and (-)-pukateine, three natural 6a(R)-1,2-methylenedioxyaporphines with different affinities for α1-adrenoceptor subtypes
(2004)
We have studied the mechanism of action of three 6a(R)-1,2- methylenedioxyaporphines as vasorelaxant compounds. The alkaloids assayed showed different affinities for the three human cloned α1- adrenoceptor (AR) subtypes ...
Expression of the gamma-globin gene is sustained by the cAMP-dependent pathway in beta-thalassaemia
(Blackwell PublishingOxfordInglaterra, 2007)
Signal Transduction Pathways as Therapeutic Target for Chagas Disease
(Bentham Science Publishers, 2019-06)
Trypanosomatids are a group of flagellated unicellular eukaryotes, which cause serious human diseases including Chagas disease (Trypanosoma cruzi), sleeping sickness (Trypanosoma brucei spp.) and Leishmaniasis (Leishmania ...
Increased glycated calmodulin in the submandibular salivary glands of streptozotocin-induced diabetic rats
(John Wiley & Sons LtdChichesterInglaterra, 2009)
Purification of n-boc-Rolipram racemate on chiral stationary phase using simulated moving bed chromatography under linear conditions
(Elsevier Science SaLausanneSuíça, 2008)
Cryopreservation of human spermatozoa with pentoxifylline improves the post-thaw agonist-induced acrosome reaction rate
(Oxford Univ PressOxfordInglaterra, 1998)
Pentoxifylline mitigates renal glycoxidative stress in obese mice by inhibiting AGE/RAGE signaling and increasing glyoxalase levels
(2020-10-01)
Aim: The pharmacological properties of pentoxifylline have been re-evaluated, particularly in chronic kidney disease in diabetes, favored by its anti-inflammatory action. Definitive evidences of renal outcomes are lacking, ...
Blame the signaling: role of cAMP for the resolution of inflammation
(Universidade Federal de Minas GeraisBrasilFAR - DEPARTAMENTO DE ANÁLISES CLÍNICAS E TOXICOLÓGICASICB - DEPARTAMENTO DE BIOQUÍMICA E IMUNOLOGIAICB - DEPARTAMENTO DE FARMACOLOGIAICB - DEPARTAMENTO DE MORFOLOGIAUFMG, 2020-09)
Uma sinalização intracelular complexa governa diferentes respostas celulares na inflamação. Estímulos extracelulares são detectados, amplificados e transduzidos através de uma rede celular dinâmica de mensageiros convertendo ...
Blame the signaling: Role of cAMP for the resolution of inflammation
(Elsevier, 2021)