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Progesterone is essential for protecting against LPS-induced pregnancy loss. LIF as a potential mediator of the anti-inflammatory effect of progesterone
(Public Library Science, 2013-02-07)
Abstract Lipopolysaccharide (LPS) administration to mice on day 7 of gestation led to 100% embryonic resorption after 24 h. In this model, nitric oxide is fundamental for the resorption process. Progesterone may be ...
Transcriptional profiling of embryos lacking the lipoprotein receptor SR-B1 reveals a regulatory circuit governing a neurodevelopmental or metabolic decision during neural tube closure
(2018)
Background: The high-density lipoprotein receptor SR-B1 mediates cellular uptake of several lipid species, including cholesterol and vitamin E. During early mouse development, SR-B1 is located in the maternal-fetal interface, ...
Implication of RANTES in the modulation of alloimmune response by progesterone during pregnancy
(Wiley Blackwell Publishing, Inc, 2007-02)
Problem: Several studies indicate that RANTES (regulated on activation, normal T cell expressed and secreted) is able to downregulate T-cell responses which suggest it might be relevant for fetal tolerance induction. ...
Lysophosphatidic acid-triggered pathways promote the acquisition of trophoblast endovascular phenotype in vitro
(Wiley-liss, Div John Wiley & Sons Inc, 2018-01)
Successful implantation and placentation requires that extravillous cytotrophoblast acquires an endovascular phenotype and remodels uterine spiral arteries. Defects in this mechanism correlate with severe obstetric ...
Vascular endothelial growth factor (VEGF) and VEGF-receptor expression in placenta of hyperglycemic pregnant women
(W B Saunders Co Ltd, 2010-09-01)
Hyperglycemia occurs in a variety of conditions such as overt diabetes, gestational diabetes and mild hyperglycemia, all of which are generally defined based on the oral glucose tolerance test and glucose profiles. Whereas ...
Granulocyte colony-stimulating factor (G-CSF) upregulates β1 integrin and increases migration of human trophoblast Swan 71 cells via PI3K and MAPK activation
(Elsevier, 2016)
Abstract: Multiple cytokines and growth factors expressed at the fetal-maternal interface are involved in the regulation of trophoblast functions and placental growth, but the role of G-CSF has not been completely established. ...
Vascular endothelial growth factor (VEGF) and VEGF-receptor expression in placenta of hyperglycemic pregnant women
(W B Saunders Co Ltd, 2010-09-01)
Hyperglycemia occurs in a variety of conditions such as overt diabetes, gestational diabetes and mild hyperglycemia, all of which are generally defined based on the oral glucose tolerance test and glucose profiles. Whereas ...
Efectividad del cerclaje cervical vs progesterona vaginal en la prevención de parto pretérmino en gestantes con insuficiencia cervical en el Hospital Belén de Trujillo durante el periodo Enero 2010 – Enero 2022
(Universidad Nacional de TrujilloPE, 2022-08-19)
El parto pretérmino se define como un nacimiento que ocurre después de las 20 semanas de gestación y antes de las 37 semanas completas, asociado con un riesgo elevado de morbimortalidad neonatal, asimismo, es un problema ...
Activation of the pi3k/akt signaling pathway by insulin-like growth factor type II stimulates the expression of marn metalloproteinase 9 in choriocarcinoma cellsLa activación de la vía de señalización pi3k/akt por el factor de crecimiento similar a la insulina tipo ii estimula la expresión del marn de la metaloproteinasa 9 en células de coriocarcinoma
(Revista Colombiana de Química, 2009)
Metalloproteinases 2 and 9 (MMP-2 and MMP-9) and MMP inhibitor-1 (TIMP-1) could contribute to the regulation of the invasive behavior of trophoblast cells, an effect that could be mediated by similar growth factor to insulin ...
Expressão gênica e protéica de receptores Toll-like em células do sangue periférico materno de gestações normais e complicadas por prematuridade
(Universidade Estadual Paulista (UNESP), 2016)