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Progesterone restores the female prostate activity in ovariectomized gerbil and may act as competitor of testosterone in intraprostatic environment
(2013-05-30)
Aims Little is known about the effect of progesterone on gerbil female prostate. It is known that normal oscillation in the progesterone and estradiol levels during the estrous cycle phases influence the morphophysiology ...
Estrogen receptors mediate rapid activation of phospholipase C pathway in the rat endometrium
(Elsevier B.V., 2011-12-20)
The aim of the present study was to investigate the activation of rapid signaling events by 17 beta-estradiol in the rat uterus. 17 beta-Estradiol induced a rapid increase of total [(3)H]-inositol phosphate accumulation ...
Efficacy of a Low Dose of Estrogen on Antioxidant Defenses and Heart Rate Variability
(Hindawi Publishing Corporation, 2014-03)
This study tested whether a low dose (40% less than the pharmacological dose of 17-β estradiol) would be as effective as the pharmacological dose to improve cardiovascular parameters and decrease cardiac oxidative stress. ...
Paxillin, a novel controller in the signaling of estrogen to FAK/N-WASP/Arp2/3 complex in breast cancer cells
(Elsevier Ireland, 2016-07-15)
Breast cancer is the major cause of cancer-related death in women. Its treatment is particularly difficult when metastasis occurs. The ability of cancer cells to move and invade the surrounding environment is the basis of ...
The Subcellular Localization and Physiological Roles of Estrogen Receptors α and β in Classical and Non-Classical Tissues
(Nova Science Publishers, 2017)
It is now firmly established that estrogens elicit a variety of rapid effects in many tissues in addition to their delayed action on gene expression in the cell nucleus. Moreover, the classic estrogen receptors have been ...
Síndrome do climatério
(2014)
Role of 2-methoxyestradiol, an Endogenous Estrogen Metabolite, in Health and Disease
(Bentham Science, 2015)
Estradiol (E-2) is a steroid hormone whose physiological actions are mainly mediated by its interaction with intracellular estrogen receptors (ER) leading to modification on the mRNA and protein synthesis in its target ...
Adjunctive antimicrobial photodynamic treatment of experimentally induced periodontitis in rats with ovariectomy
(2013-04-01)
Background: The aim of this study is to compare antimicrobial photodynamic therapy (aPDT) as an adjunctive therapy to scaling and root planing (SRP) for the treatment of experimentally induced periodontitis in rats with ...
Adjunctive antimicrobial photodynamic treatment of experimentally induced periodontitis in rats with ovariectomy
(2013-04-01)
Background: The aim of this study is to compare antimicrobial photodynamic therapy (aPDT) as an adjunctive therapy to scaling and root planing (SRP) for the treatment of experimentally induced periodontitis in rats with ...
Nitric oxide plays a key role in ovariectomy-induced apoptosis in anterior pituitary: Interplay between nitric oxide pathway and estrogen
(Public Library of Science, 2016-09)
Changes in the estrogenic status produce deep changes in pituitary physiology, mainly because estrogens (E2) are one of the main regulators of pituitary cell population. Also, E2 negatively regulate pituitary neuronal ...