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Expression of teneurins is associated with tumor differentiation and patient survival in ovarian cancer
(PLoS, 2017)
Teneurins are a family of highly conserved pair-rule proteins involved in morphogenesis and development of the central nervous system. Their function in adult tissues and in disease is largely unknown. Recent evidence ...
Niveles de cox-2 en cáncer ovárico epitelial : efecto de TGF-β1 y NGF en los niveles de cox-2, PGE2 y VEGF en líneas celulares de ovario
(Universidad de Chile, 2015)
El cáncer ovárico epitelial (COE) es la primera causa de muerte por neoplasias ginecológicas en países desarrollados como Canadá, EE.UU e Israel. Específicamente en Chile, es la segunda causa de muerte por neoplasias ...
QSAR Classification of Anticancer Heterocyclichydrazones with Reactivity Descriptors
(IGI GLOBAL, 2021-01)
In this study, validated PLS-DA models that discriminate heterocyclichydrazones with potentanticancer activity (GI50/IC50<50x10-6M) from those with low activity (GI50/IC50>=50x10-6M) against the cancer cell lines HCT-116 ...
Sexual differentiation and reproductive development of female rat offspring after paternal exposure to the anti-tumor pharmaceutical cisplatin
(2016-04-01)
Cisplatin (CP) is used to treat a number of cancers, including testicular cancer. Studies indicate that CP-treatment can impair spermatogenesis in humans and rodents by germ cell DNA binding, through different modes of ...