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Synthesis, characterization and in vitro antifungal evaluation of novel benzimidazo [1,2-c]quinazolines
(2006)
The synthesis of a series of new benzimidazo[1,2-c]quinazolines starting from 2-nitrobenzaldehyde and o-phenylendiamine is described. The structure elucidation of the products is based on detailed NMR analysis of experiments ...
SYNTHESIS, CHARACTERIZATION AND IN VITRO ANTIFUNGAL EVALUATION OF NOVEL BENZIMIDAZO[1,2-c]QUINAZOLINES
(Sociedad Chilena de Química, 2006)
Synthesis, characterization and in vitro antifungal elevation of novel benzimidazo [1,2-c]quinazolines
(Sociedad Chilena de Química, 2006)
The synthesis of a series of new benzimidazo [1,2-c]quinazolines starting from 2-nitrobenzaldehyde and o-phenylendiamine is decsribe. The structure elucidation of the products is based on detailed NMR analysis of experiments ...
Synthesis, 2D-QSAR studies and biological evaluation of quinazoline derivatives as potent anti-trypanosoma cruzi agents
(Bentham Science Publishers, 2018-10)
Background: Chagas disease affects about 7 million people worldwide. Only two drugs are currently available for the treatment for this parasite disease, namely, benznidazol (Bzn) and nifurtimox (Nfx). Both drugs have limited ...
Solvent-free synthesis of 6-arylbenzimidazo[1,2-c]quinazolines under microwave irradiation
(GEORG THIEME VERLAG KG, 2004-02-18)
The syntheses of 2-(2-nitrophenyl)-1-benzoyl-1H-benzimidazole derivatives 5-9 and their reduction to the corresponding 2-benzimidazoylbenzamides 10-13 are described. Compounds 10-13 were cleanly and efficiently converted ...
Síntese de heterociclos nitrogenados através de reações de funcionalização C-H de azaarenos e avaliação da atividade antiparasitária
(Universidade Federal de São CarlosUFSCarPrograma de Pós-Graduação em Química - PPGQCâmpus São Carlos, 2022-01-28)
The neglected diseases caused by parasites, such as Chagas´ disease, sleeping sickness and leishmaniasis, affect thousands of people every year, mainly in tropical and underdeveloped countries. Due to the lack of efficient ...
Deleterious effects of VEGFR2 and RET inhibition in a preclinical model of Parkinson’s disease
(Humana Press Inc., 2018)