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In vitro binding affinities of a series of flavonoids for mu-opioid receptors. Antinociceptive effect of the synthetic flavonoid 3,3-dibromoflavanone in mice
(Elsevier, 2013-05)
The pharmacotherapy for the treatment of pain is an active area of investigation. There are effective drugs to treat this problem, but there is also a need to find alternative treatments free of undesirable side effects. ...
Flavonoids as GABAA receptor ligands: the whole story?
(Dove Medical Press, 2012-01)
Benzodiazepines are the most widely prescribed class of psychoactive drugs in current therapeutic use, despite the important unwanted side effects that they produce, such as sedation, myorelaxation, ataxia, amnesia, and ...
Anti-African trypanocidal and antimalarial activity of natural flavonoids, dibenzoylmethanes and synthetic analogues
(Wiley-blackwellHobokenEUA, 2009)
Avaliação da atividade antioxidante de extratos etanólicos de resíduos provenientes da fabricação de vinho
(Universidade Tecnológica Federal do ParanáPato Branco, 2014-02-14)
The search for natural products that perform efficiently the antioxidant activity in foods is having a lot of attention in research today. The main compounds that can act with this action, are phenolic compounds, these can ...
Avaliação da atividade antioxidante do extrato etanólico das folhas da espécie Drimys brasiliensis Miers (Winteraceae)
(Universidade Tecnológica Federal do ParanáPato BrancoBrasilDepartamento Acadêmico de QuímicaQuímicaUTFPR, 2015-11-17)
The species Drimys brasiliensis Miers, belonging to Winteraceae family whose genre can be found in Brazil, from Bahia to Rio Grande do Sul, and in turn more common in riparian forests and in the deciduous forests of altitude, ...
ANTI-ALZHEIMER ACTIVITY OF SUBSTANCES FROM NATURAL PRODUCTS AND OF SYNTHETIC ORIGIN: SOME IMPORTANT EXAMPLES OF THE LAST 20 YEARS.
(Soc Brasileira Quimica, 2022-02-04)
Alzheimer's disease has about 9.9 million new cases annually, according to World Health Organization. Due to the increasing incidence of people affected by AD and the absence of an efficient treatment or cure so far, many ...
Cholesterol oxidation: Health hazard and the role of antioxidants in prevention
(Sociedad de Biología de Chile, 2003)
Analytical determinations of luteolin
(Wiley Blackwell Publishing, Inc, 2021-03)
Plants, through the photosynthesis process, produce the substances necessary for all the life cycles of nature, which are called "primary metabolites." Moreover, there are some plants that synthesize, in addition to these, ...
Flavonoids from Pterogyne nitens as Zika virus NS2B-NS3 protease inhibitors
(2021-04-01)
Although the widespread epidemic of Zika virus (ZIKV) and its neurological complications are well-known there are still no approved drugs available to treat this arboviral disease or vaccine to prevent the infection. ...