bachelorThesis
Avaliação da atividade antioxidante do extrato etanólico das folhas da espécie Drimys brasiliensis Miers (Winteraceae)
Fecha
2015-11-17Registro en:
AZEVEDO, Monique Bernardo. Avaliação da atividade antioxidante do extrato etanólico das folhas da espécie Drimys brasiliensis Miers (Winteraceae). 2015. 44 f. Trabalho de Conclusão de Curso (Graduação) - Universidade Tecnológica Federal do Paraná, Pato Branco, 2015.
Autor
Azevedo, Monique Bernardo
Resumen
The species Drimys brasiliensis Miers, belonging to Winteraceae family whose genre can be found in Brazil, from Bahia to Rio Grande do Sul, and in turn more common in riparian forests and in the deciduous forests of altitude, is known for its high potential index therapeutic and is used in folk medicine as a stimulant, antispasmodic, antidiarrheal, antipyretic, antibacterial, for the treatment of asthma and bronchitis, and also have insecticides and nutritional properties, since its bark acts as a substitute for black pepper kingdom. Considering that the study of bioactive plans encourage the interest of the food industry, cosmetics and pharmaceuticals, not only for their high therapeutic potential index, but also because it is possible natural sources of bioactive compounds with antioxidant power, able to replace synthetic antioxidants used in these industries by natural source of antioxidants. Given that the objective of this study was to evaluate the antioxidant activity of ethanol extract of the species Drimys brasiliensis Miers, through the determination of the content of phenolic compounds, the determination of total flavonoid content and the sequestering methods of free radicals ABTS and DPPH, expressed as EC50. The results obtained were 110.9958 ± 3.1915 mg EAG g-1 sample for the content of phenolic compounds, 59.7891 ± 7.5183 mg EQ g-1 sample to the levels of total flavonoids 6264.7143 ± 347.3369 μmol TEAC g-1 sample through sequestration of free radical ABTS method and a concentration of 0.1598 ± 0.0096 mg mL-1 by sequestering the free radical DPPH method, expressed as EC50, the concentration which indicates minimum sample required to reduce by 50% the free radicals. The results obtained for the evaluation of the antioxidant activity of the species Drimys brasiliensis Miers, taking into account the missing or bit study found that effect for this species, thus making it possible that this species is a likely source of natural antioxidants that has great potential to become a possible replacement for synthetic antioxidant used in industries.